diff --git a/pkgs/development/python-modules/eth-abi/default.nix b/pkgs/development/python-modules/eth-abi/default.nix
index 43d5401ce58f..03c5cc63127b 100644
--- a/pkgs/development/python-modules/eth-abi/default.nix
+++ b/pkgs/development/python-modules/eth-abi/default.nix
@@ -12,19 +12,19 @@
 
 buildPythonPackage rec {
   pname = "eth-abi";
-  version = "3.0.1";
+  version = "4.1.0";
   disabled = pythonOlder "3.7";
 
   src = fetchFromGitHub {
     owner = "ethereum";
     repo = "eth-abi";
     rev = "v${version}";
-    hash = "sha256-xrZpT/9zwDtjSwSPDDse+Aq8plPm26OR/cIrliZUpLY=";
+    hash = "sha256-CGAfu3Ovz2WPJOD+4W2+cOAz+wYvuIyFL333Jw66ozA=";
   };
 
   postPatch = ''
     substituteInPlace setup.py \
-      --replace "parsimonious>=0.8.0,<0.9.0" "parsimonious"
+      --replace "parsimonious>=0.9.0,<0.10.0" "parsimonious"
   '';
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/web3/default.nix b/pkgs/development/python-modules/web3/default.nix
index 0b285bd514d1..1c88f51345de 100644
--- a/pkgs/development/python-modules/web3/default.nix
+++ b/pkgs/development/python-modules/web3/default.nix
@@ -37,10 +37,6 @@ buildPythonPackage rec {
     hash = "sha256-p3Dpmb0BST1nbh42q/eK/DjQqoIPHvNr2KllRpTgFFw=";
   };
 
-  nativeBuildInputs = [
-    pythonRelaxDepsHook
-  ];
-
   propagatedBuildInputs = [
     aiohttp
     eth-abi