diff --git a/pkgs/development/cuda-modules/packages/cuda_nvcc.nix b/pkgs/development/cuda-modules/packages/cuda_nvcc.nix
index 41da5b0f8c6c..993c92c778de 100644
--- a/pkgs/development/cuda-modules/packages/cuda_nvcc.nix
+++ b/pkgs/development/cuda-modules/packages/cuda_nvcc.nix
@@ -4,6 +4,7 @@
   buildRedist,
   cudaAtLeast,
   cudaOlder,
+  cuda_cccl,
   lib,
   libnvvm,
 }:
@@ -111,6 +112,16 @@ buildRedist (finalAttrs: {
             '$(_TARGET_SIZE_)' \
             ""
       ''
+      # CUDA 13.0+ introduced
+      # SYSTEM_INCLUDES +=  "-isystem" "$(TOP)/$(_TARGET_DIR_)/include/cccl" $(_SPACE_)
+      # so we need to make sure to patch the reference to cccl.
+      + lib.optionalString (cudaAtLeast "13.0") ''
+        nixLog "patching nvcc.profile to include correct path to cccl"
+        substituteInPlace "''${!outputBin:?}/bin/nvcc.profile" \
+          --replace-fail \
+            '$(TOP)/$(_TARGET_DIR_)/include/cccl' \
+            "${lib.getOutput "include" cuda_cccl}/include"
+      ''
       # Unconditional patching to switch to the correct include paths.
       # NOTE: _TARGET_DIR_ appears to be used for the target architecture, which is relevant for cross-compilation.
       + ''