diff --git a/pkgs/development/python-modules/lmstudio/default.nix b/pkgs/development/python-modules/lmstudio/default.nix
new file mode 100644
index 000000000000..10fce8805d42
--- /dev/null
+++ b/pkgs/development/python-modules/lmstudio/default.nix
@@ -0,0 +1,94 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+
+  # build-system
+  pdm-backend,
+
+  # dependencies
+  anyio,
+  httpx,
+  httpx-ws,
+  msgspec,
+  typing-extensions,
+
+  # tests
+  pytest-asyncio,
+  pytestCheckHook,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "lmstudio";
+  version = "1.5.0";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "lmstudio-ai";
+    repo = "lmstudio-python";
+    tag = finalAttrs.version;
+    hash = "sha256-3LOoCWoQ7eXRPXHRio9Rtle07HcV3ZrWkrtVVY6mvfI=";
+  };
+
+  build-system = [
+    pdm-backend
+  ];
+
+  dependencies = [
+    anyio
+    httpx
+    httpx-ws
+    msgspec
+    typing-extensions
+  ];
+
+  pythonImportsCheck = [ "lmstudio" ];
+
+  nativeCheckInputs = [
+    pytest-asyncio
+    pytestCheckHook
+  ];
+
+  disabledTests = [
+    # lmstudio.LMStudioRuntimeError: Local API host port is not yet resolved.
+    "test_session_disconnected_async"
+  ];
+
+  disabledTestPaths = [
+    # ModuleNotFoundError: No module named 'pytest_subtests'
+    "tests/async/test_model_catalog_async.py"
+    "tests/sync/test_model_catalog_sync.py"
+    "tests/test_inference.py"
+
+    # lmstudio.LMStudioRuntimeError: Local API host port is not yet resolved.
+    "tests/async/test_embedding_async.py"
+    "tests/async/test_images_async.py"
+    "tests/async/test_inference_async.py"
+    "tests/async/test_llm_async.py"
+    "tests/async/test_model_handles_async.py"
+    "tests/async/test_repository_async.py"
+    "tests/async/test_sdk_bypass_async.py"
+    "tests/sync/test_embedding_sync.py"
+    "tests/sync/test_images_sync.py"
+    "tests/sync/test_inference_sync.py"
+    "tests/sync/test_llm_sync.py"
+    "tests/sync/test_model_handles_sync.py"
+    "tests/sync/test_repository_sync.py"
+    "tests/sync/test_sdk_bypass_sync.py"
+    "tests/test_convenience_api.py"
+    "tests/test_logging.py"
+    "tests/test_plugin_examples.py"
+    "tests/test_sessions.py"
+    "tests/test_timeouts.py"
+  ];
+
+  __darwinAllowLocalNetworking = true;
+
+  meta = {
+    description = "LM Studio Python SDK";
+    homepage = "https://github.com/lmstudio-ai/lmstudio-python";
+    changelog = "https://github.com/lmstudio-ai/lmstudio-python/releases/tag/${finalAttrs.src.tag}";
+    license = lib.licenses.mit;
+    maintainers = with lib.maintainers; [ GaetanLepage ];
+  };
+})
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 426268b1a572..59ff11bcb22c 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -9209,6 +9209,8 @@ self: super: with self; {
 
   lmnotify = callPackage ../development/python-modules/lmnotify { };
 
+  lmstudio = callPackage ../development/python-modules/lmstudio { };
+
   lmtpd = callPackage ../development/python-modules/lmtpd { };
 
   lnkparse3 = callPackage ../development/python-modules/lnkparse3 { };