diff --git a/pkgs/development/python-modules/qscintilla-qt5/default.nix b/pkgs/development/python-modules/qscintilla-qt5/default.nix
index 70ee43089134..b3fb0644824e 100644
--- a/pkgs/development/python-modules/qscintilla-qt5/default.nix
+++ b/pkgs/development/python-modules/qscintilla-qt5/default.nix
@@ -2,51 +2,68 @@
 , pythonPackages
 , qscintilla
 , qtbase
+, qmake
+, qtmacextras ? null
+, stdenv
 }:
 
 let
-  inherit (pythonPackages) buildPythonPackage isPy3k python sip_4 pyqt5;
+  inherit (pythonPackages) buildPythonPackage isPy3k python sip sipbuild pyqt5 pyqt-builder;
 in buildPythonPackage rec {
   pname = "qscintilla";
   version = qscintilla.version;
   src = qscintilla.src;
-  format = "other";
+  format = "pyproject";
 
   disabled = !isPy3k;
 
-  nativeBuildInputs = [ sip_4 qtbase ];
-  buildInputs = [ qscintilla ];
-  propagatedBuildInputs = [ pyqt5 ];
+  nativeBuildInputs = [ sip qmake pyqt-builder ];
+  buildInputs = [ qtbase qscintilla ];
+  propagatedBuildInputs = [ pyqt5 pyqt5 ] ++ lib.optional (stdenv.isDarwin) qtmacextras;
 
   dontWrapQtApps = true;
 
+  # postPatch = ''
+  #   substituteInPlace Python/configure.py \
+  #     --replace \
+  #     "target_config.py_module_dir" \
+  #     "'$out/${python.sitePackages}'"
+  # '';
+  #
+
+  qsciFeaturesDir = qscintilla + "/mkspecs/features";
+  qsciIncludeDir = qscintilla + "/include";
+  qsciLibraryDir = qscintilla + "/lib";
+  sipIncludeDirs = pyqt5 + "/" + python.sitePackages + "/PyQt5/bindings";
+  apiDir = qscintilla + "/share";
+
   postPatch = ''
-    substituteInPlace Python/configure.py \
-      --replace \
-      "target_config.py_module_dir" \
-      "'$out/${python.sitePackages}'"
-  '';
-
-  preConfigure = ''
-    # configure.py will look for this folder
-    mkdir -p $out/share/sip/PyQt5
-
     cd Python
-    substituteInPlace configure.py \
-      --replace "qmake = {'CONFIG': 'qscintilla2'}" "qmake = {'CONFIG': 'qscintilla2', 'QT': 'widgets printsupport'}"
-    ${python.executable} ./configure.py \
-      --pyqt=PyQt5 \
-      --destdir=$out/${python.sitePackages}/PyQt5 \
-      --stubsdir=$out/${python.sitePackages}/PyQt5 \
-      --apidir=$out/api/${python.libPrefix} \
-      --qsci-incdir=${qscintilla}/include \
-      --qsci-featuresdir=${qscintilla}/mkspecs/features \
-      --qsci-libdir=${qscintilla}/lib \
-      --pyqt-sipdir=${pyqt5}/${python.sitePackages}/PyQt5/bindings \
-      --qsci-sipdir=$out/share/sip/PyQt5 \
-      --sip-incdir=${sip_4}/include
+    cp pyproject-qt5.toml pyproject.toml
+    echo '[tool.sip.project]' >> pyproject.toml
+    echo 'sip-include-dirs = [ "${sipIncludeDirs}" ]' >> pyproject.toml
   '';
 
+  dontConfigure = true;
+    # substituteInPlace configure.py \
+    #   --replace "qmake = {'CONFIG': 'qscintilla2'}" "qmake = {'CONFIG': 'qscintilla2', 'QT': 'widgets printsupport'}"
+    # ${python.executable} ./configure.py \
+    #   --pyqt=PyQt5 \
+    #   --destdir=$out/${python.sitePackages}/PyQt5 \
+    #   --stubsdir=$out/${python.sitePackages}/PyQt5 \
+    #   --apidir=$out/api/${python.libPrefix} \
+    #   --qsci-incdir=${qscintilla}/include \
+    #   --qsci-featuresdir=${qscintilla}/mkspecs/features \
+    #   --qsci-libdir=${qscintilla}/lib \
+    #   --pyqt-sipdir=${pyqt5}/${python.sitePackages}/PyQt5/bindings \
+    #   --qsci-sipdir=$out/share/sip/PyQt5 \
+    #   --sip-incdir=${sip}/include
+    #
+
+  build = "sip-install --qsci-features-dir ${qsciFeaturesDir} --qsci-include-dir ${qsciIncludeDir} \
+           --qsci-library-dir ${qsciLibraryDir} --api-dir ${apiDir}" + lib.optionalString stdenv.isDarwin
+           " --qmake-setting 'QT += widgets'";
+
   postInstall = ''
     # Needed by pythonImportsCheck to find the module
     export PYTHONPATH="$out/${python.sitePackages}:$PYTHONPATH"