diff --git a/pkgs/applications/audio/musescore/default.nix b/pkgs/applications/audio/musescore/default.nix
index c2a2e7b96031..4b784272c35b 100644
--- a/pkgs/applications/audio/musescore/default.nix
+++ b/pkgs/applications/audio/musescore/default.nix
@@ -27,6 +27,8 @@ mkDerivation rec {
   ];
 
   qtWrapperArgs = [
+    # MuseScore JACK backend loads libjack at runtime.
+    "--prefix LD_LIBRARY_PATH : ${lib.makeLibraryPath [ libjack2 ]}"
     # Work around crash on update from 3.4.2 to 3.5.0
     # https://bugreports.qt.io/browse/QTBUG-85967
     "--set QML_DISABLE_DISK_CACHE 1"