diff --git a/pkgs/development/compilers/swift/compiler/default.nix b/pkgs/development/compilers/swift/compiler/default.nix
index c71a22589d9f..5bb32d8496cd 100644
--- a/pkgs/development/compilers/swift/compiler/default.nix
+++ b/pkgs/development/compilers/swift/compiler/default.nix
@@ -523,8 +523,10 @@ stdenv.mkDerivation {
     # Add appleSwiftCore to the search paths. Adding the whole SDK results in build failures.
     OLD_NIX_SWIFTFLAGS_COMPILE="$NIX_SWIFTFLAGS_COMPILE"
     OLD_NIX_LDFLAGS="$NIX_LDFLAGS"
+    OLD_NIX_CFLAGS_COMPILE="$NIX_CFLAGS_COMPILE"
     export NIX_SWIFTFLAGS_COMPILE=" -I ${appleSwiftCore}/lib/swift"
     export NIX_LDFLAGS+=" -L ${appleSwiftCore}/lib/swift"
+    export NIX_CFLAGS_COMPILE+=" -Wno-error=unguarded-availability"
   ''
   + ''
 
@@ -568,6 +570,7 @@ stdenv.mkDerivation {
     # Restore search paths to remove appleSwiftCore.
     export NIX_SWIFTFLAGS_COMPILE="$OLD_NIX_SWIFTFLAGS_COMPILE"
     export NIX_LDFLAGS="$OLD_NIX_LDFLAGS"
+    export NIX_CFLAGS_COMPILE="$OLD_NIX_CFLAGS_COMPILE"
   ''
   + ''
 
diff --git a/pkgs/development/compilers/swift/wrapper/wrapper.sh b/pkgs/development/compilers/swift/wrapper/wrapper.sh
index 21fba5395123..2017f580cef2 100644
--- a/pkgs/development/compilers/swift/wrapper/wrapper.sh
+++ b/pkgs/development/compilers/swift/wrapper/wrapper.sh
@@ -248,6 +248,9 @@ fi
 # TODO: If we ever need to expand functionality of this hook, it may no longer
 # be compatible with Swift. Right now, it is only used on Darwin to force
 # -target, which also happens to work with Swift.
+# As of 369cc5c66b1efdbca2f136aa0055fedca1117304 (#445119), this hook also sets
+# the -Werror=unguarded-availability flag, which Swift can't accept. We prefix
+# that flag with -Xcc in the for loop below
 if [[ -e $cc_wrapper/nix-support/add-local-cc-cflags-before.sh ]]; then
     source $cc_wrapper/nix-support/add-local-cc-cflags-before.sh
 fi
@@ -262,7 +265,7 @@ for ((i=0; i < ${#extraBefore[@]}; i++));do
         # TODO: Assumes macOS.
         extraBefore[i]="${extraBefore[i]/-apple-darwin/-apple-macosx${MACOSX_DEPLOYMENT_TARGET:-11.0}}"
         ;;
-    -march=*|-mcpu=*|-mfloat-abi=*|-mfpu=*|-mmode=*|-mthumb|-marm|-mtune=*)
+    -march=*|-mcpu=*|-mfloat-abi=*|-mfpu=*|-mmode=*|-mthumb|-marm|-mtune=*|-Werror=*)
         [[ i -gt 0 && ${extraBefore[i-1]} == -Xcc ]] && continue
         extraBefore=(
             "${extraBefore[@]:0:i}"