diff --git a/pkgs/applications/graphics/hydrus/default.nix b/pkgs/applications/graphics/hydrus/default.nix
index 6a31bfd0280d..611033c5906a 100644
--- a/pkgs/applications/graphics/hydrus/default.nix
+++ b/pkgs/applications/graphics/hydrus/default.nix
@@ -6,18 +6,20 @@
 , enableSwftools ? false
 , swftools
 , python3Packages
+, qtbase
+, qtcharts
 }:
 
 python3Packages.buildPythonPackage rec {
   pname = "hydrus";
-  version = "503";
+  version = "519";
   format = "other";
 
   src = fetchFromGitHub {
     owner = "hydrusnetwork";
     repo = "hydrus";
     rev = "refs/tags/v${version}";
-    hash = "sha256-nJn5EphbmVYAAOisV3fym/nHlJl/aPZ2Iyp+Z2/N3Jc=";
+    hash = "sha256-q5pPRMBuB6hqDGuOl0kMyXjMKze5dw+3kdmA2FPJTPU=";
   };
 
   nativeBuildInputs = [
@@ -25,6 +27,11 @@ python3Packages.buildPythonPackage rec {
     python3Packages.mkdocs-material
   ];
 
+  buildInputs = [
+    qtbase
+    qtcharts
+  ];
+
   propagatedBuildInputs = with python3Packages; [
     beautifulsoup4
     cbor2
@@ -37,8 +44,10 @@ python3Packages.buildPythonPackage rec {
     opencv4
     pillow
     psutil
+    pympler
     pyopenssl
-    pyside2
+    pyqt6
+    pyqt6-charts
     pysocks
     python-dateutil
     python3Packages.mpv
@@ -82,6 +91,7 @@ python3Packages.buildPythonPackage rec {
     -e TestHydrusServer \
     -e TestHydrusSessions \
     -e TestServer \
+    -e TestClientMetadataMigration \
   '';
 
   outputs = [ "out" "doc" ];
diff --git a/pkgs/development/python-modules/pyqt6-charts.nix b/pkgs/development/python-modules/pyqt6-charts.nix
new file mode 100644
index 000000000000..66df9bbf0fbc
--- /dev/null
+++ b/pkgs/development/python-modules/pyqt6-charts.nix
@@ -0,0 +1,77 @@
+{ lib
+, buildPythonPackage
+, fetchPypi
+, sip
+, pyqt-builder
+, qt6Packages
+, pythonOlder
+, pyqt6
+, python
+}:
+
+buildPythonPackage rec {
+  pname = "PyQt6_Charts";
+  version = "6.4.0";
+  format = "pyproject";
+
+  disabled = pythonOlder "3.6";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "sha256-tG6xKEBRagOcNvcLs/hCMzf5j94ma1gs6tQEm3e0P2Q=";
+  };
+
+  # fix include path and increase verbosity
+  postPatch = ''
+    sed -i \
+      '/\[tool.sip.project\]/a\
+      verbose = true\
+      sip-include-dirs = [\"${pyqt6}/${python.sitePackages}/PyQt6/bindings\"]' \
+      pyproject.toml
+  '';
+
+  enableParallelBuilding = true;
+  # HACK: paralellize compilation of make calls within pyqt's setup.py
+  # pkgs/stdenv/generic/setup.sh doesn't set this for us because
+  # make gets called by python code and not its build phase
+  # format=pyproject means the pip-build-hook hook gets used to build this project
+  # pkgs/development/interpreters/python/hooks/pip-build-hook.sh
+  # does not use the enableParallelBuilding flag
+  preBuild = ''
+    export MAKEFLAGS+="''${enableParallelBuilding:+-j$NIX_BUILD_CORES}"
+  '';
+
+  dontWrapQtApps = true;
+
+  nativeBuildInputs = with qt6Packages; [
+    qtcharts
+    sip
+    qmake
+    pyqt-builder
+  ];
+
+  buildInputs = with qt6Packages; [
+    qtcharts
+  ];
+
+  propagatedBuildInputs = [
+    pyqt6
+  ];
+
+  dontConfigure = true;
+
+  # has no tests
+  doCheck = false;
+
+  pythonImportsCheck = [
+    "PyQt6.QtCharts"
+  ];
+
+  meta = with lib; {
+    description = "Python bindings for Qt6 QtCharts";
+    homepage = "https://riverbankcomputing.com/";
+    license = licenses.gpl3Only;
+    platforms = platforms.mesaPlatforms;
+    maintainers = with maintainers; [ dandellion ];
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 0c8f45628658..1928fdf2df8d 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -30181,7 +30181,7 @@ with pkgs;
 
   hydrus = python3Packages.callPackage ../applications/graphics/hydrus {
     inherit miniupnpc swftools;
-    inherit (qt5) wrapQtAppsHook;
+    inherit (qt6) wrapQtAppsHook qtbase qtcharts;
   };
 
   jetbrains = (recurseIntoAttrs (callPackages ../applications/editors/jetbrains {
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 979731d96349..f607af588cd8 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8751,6 +8751,8 @@ self: super: with self; {
 
   pyqt6 = callPackage ../development/python-modules/pyqt/6.x.nix { };
 
+  pyqt6-charts = callPackage ../development/python-modules/pyqt6-charts.nix { };
+
   pyqt6-sip = callPackage ../development/python-modules/pyqt/pyqt6-sip.nix { };
 
   pyqt6-webengine = callPackage ../development/python-modules/pyqt6-webengine.nix { };