diff --git a/pkgs/by-name/op/opshin/package.nix b/pkgs/by-name/op/opshin/package.nix
index d7fdf72a8163..7a1a9801eb1f 100644
--- a/pkgs/by-name/op/opshin/package.nix
+++ b/pkgs/by-name/op/opshin/package.nix
@@ -1,11 +1,12 @@
-{ lib
-, fetchFromGitHub
-, python3
+{
+  lib,
+  fetchFromGitHub,
+  python3,
 }:
 
 python3.pkgs.buildPythonApplication rec {
   pname = "opshin";
-  version = "0.20.0";
+  version = "0.21.2";
 
   format = "pyproject";
 
@@ -13,7 +14,7 @@ python3.pkgs.buildPythonApplication rec {
     owner = "OpShin";
     repo = "opshin";
     rev = version;
-    hash = "sha256-fJlPeVAuEf80FVxdXnaKASLmjMEgz6ysXenUY72+sos=";
+    hash = "sha256-YBdYF04iKUwIZncqyEDalU+YN6/qwlx/vQDzZ19GaPU=";
   };
 
   propagatedBuildInputs = with python3.pkgs; [
@@ -27,6 +28,11 @@ python3.pkgs.buildPythonApplication rec {
     ordered-set
   ];
 
+  pythonRelaxDeps = [
+    "pluthon"
+    "uplc"
+  ];
+
   meta = with lib; {
     description = "Simple pythonic programming language for Smart Contracts on Cardano";
     homepage = "https://opshin.dev";
diff --git a/pkgs/development/python-modules/mnemonic/default.nix b/pkgs/development/python-modules/mnemonic/default.nix
index 839367cc8e31..4250e048430e 100644
--- a/pkgs/development/python-modules/mnemonic/default.nix
+++ b/pkgs/development/python-modules/mnemonic/default.nix
@@ -3,20 +3,23 @@
   buildPythonPackage,
   fetchFromGitHub,
   pytestCheckHook,
+  poetry-core,
 }:
 
 buildPythonPackage rec {
   pname = "mnemonic";
-  version = "0.20";
-  format = "setuptools";
+  version = "0.21";
+  pyproject = true;
 
   src = fetchFromGitHub {
     owner = "trezor";
-    repo = "python-${pname}";
+    repo = "python-mnemonic";
     rev = "v${version}";
-    hash = "sha256-YYgWlYfVd1iALOziaUI8uVYjJDCIVk/dXcUmJd2jcvQ=";
+    hash = "sha256-D1mS/JQhefYmwrShfWR9SdiGsBUM+jmuCkfWix9tDOU=";
   };
 
+  build-system = [ poetry-core ];
+
   nativeCheckInputs = [ pytestCheckHook ];
 
   pythonImportsCheck = [ "mnemonic" ];
diff --git a/pkgs/development/python-modules/pluthon/default.nix b/pkgs/development/python-modules/pluthon/default.nix
index 537eebe52a50..3467d9b21314 100644
--- a/pkgs/development/python-modules/pluthon/default.nix
+++ b/pkgs/development/python-modules/pluthon/default.nix
@@ -1,6 +1,7 @@
 {
   lib,
   fetchFromGitHub,
+  fetchpatch2,
   buildPythonPackage,
   setuptools,
   pythonOlder,
@@ -12,7 +13,7 @@
 
 buildPythonPackage rec {
   pname = "pluthon";
-  version = "0.4.6";
+  version = "0.5.3";
 
   format = "pyproject";
 
@@ -20,9 +21,18 @@ buildPythonPackage rec {
     owner = "OpShin";
     repo = "pluthon";
     rev = version;
-    hash = "sha256-ZmBkbglSbBfVhA4yP0tJdwpJiFpJ7vX0A321ldQF0lA=";
+    hash = "sha256-pX/XPZJQZaSY06nLLEvhf+1LEqYG3CdgPV/3Q6XOzTs=";
   };
 
+  patches = [
+    (fetchpatch2 {
+      name = "pluthon-bump-uplc.patch";
+      # https://github.com/OpShin/pluthon/pull/21
+      url = "https://github.com/OpShin/pluthon/commit/4b0a40223f253643056cab12231264c5beffc666.patch?full_index=1";
+      hash = "sha256-dO9JaIpkugZFKsr3Hd0cFCy7K+cmf77UfrdkZ+sGQtA=";
+    })
+  ];
+
   propagatedBuildInputs = [
     setuptools
     uplc
diff --git a/pkgs/development/python-modules/pycardano/default.nix b/pkgs/development/python-modules/pycardano/default.nix
index cc1f79c9b2c5..973b84f4c035 100644
--- a/pkgs/development/python-modules/pycardano/default.nix
+++ b/pkgs/development/python-modules/pycardano/default.nix
@@ -7,6 +7,7 @@
   cachetools,
   cbor2,
   cose,
+  docker,
   ecpy,
   frozendict,
   frozenlist,
@@ -33,7 +34,7 @@ let
 in
 buildPythonPackage rec {
   pname = "pycardano";
-  version = "0.10.0";
+  version = "0.11.1";
 
   format = "pyproject";
 
@@ -41,15 +42,15 @@ buildPythonPackage rec {
     owner = "Python-Cardano";
     repo = "pycardano";
     rev = "v${version}";
-    hash = "sha256-LP/W8IC2del476fGFq10VMWwMrbAoCCcZOngA8unBM0=";
+    hash = "sha256-OWm6ztt3s3DUbxDZqpvwTO6XwdY/57AI6Bc6x6kxH7k=";
   };
 
-
   propagatedBuildInputs = [
     blockfrost-python
     cachetools
     cbor2
     cose_0_9_dev8
+    docker
     ecpy
     frozendict
     frozenlist
diff --git a/pkgs/development/python-modules/uplc/default.nix b/pkgs/development/python-modules/uplc/default.nix
index 8d93cd592626..bc2111a78ca5 100644
--- a/pkgs/development/python-modules/uplc/default.nix
+++ b/pkgs/development/python-modules/uplc/default.nix
@@ -15,7 +15,7 @@
 
 buildPythonPackage rec {
   pname = "uplc";
-  version = "0.6.9";
+  version = "1.0.4";
 
   format = "pyproject";
 
@@ -23,10 +23,9 @@ buildPythonPackage rec {
     owner = "OpShin";
     repo = "uplc";
     rev = version;
-    hash = "sha256-djJMNXijMVzMVzw8NZSe3YFRGyAPqdvr0P374Za5XkU=";
+    hash = "sha256-Mio6VVgQKy1GMeHNk0DITks9Nhr3lA1t7zewu9734j4=";
   };
 
-
   propagatedBuildInputs = [
     setuptools
     poetry-core