diff --git a/pkgs/by-name/sp/spades/package.nix b/pkgs/by-name/sp/spades/package.nix
index 25424578ac48..c79115d4ad49 100644
--- a/pkgs/by-name/sp/spades/package.nix
+++ b/pkgs/by-name/sp/spades/package.nix
@@ -4,6 +4,7 @@
   bzip2,
   cmake,
   fetchFromGitHub,
+  fetchpatch2,
   ncurses,
   python3,
   readline,
@@ -20,6 +21,16 @@ stdenv.mkDerivation (finalAttrs: {
     hash = "sha256-BlZjfZKtCm1kWNPjdth3pYFN0plU7xfTsFotPefzzMY=";
   };
 
+  patches = [
+    # Add missing <cstdint> for uint{8,64}_t to fix build with gcc 15.
+    (fetchpatch2 {
+      url = "https://github.com/ablab/spades/commit/10b6af96ead72fdb19e8e524aa24bdcff9986e76.patch?full_index=1";
+      stripLen = 2;
+      extraPrefix = "";
+      hash = "sha256-yAQVqE6DwPe+GZ4VR1cGytaO8NmHz6TUG7EdtbxIuTU=";
+    })
+  ];
+
   sourceRoot = "${finalAttrs.src.name}/src";
 
   cmakeFlags = [