diff --git a/pkgs/applications/misc/cherrytree/default.nix b/pkgs/applications/misc/cherrytree/default.nix
index 0ce89afa6cea..585f62178611 100644
--- a/pkgs/applications/misc/cherrytree/default.nix
+++ b/pkgs/applications/misc/cherrytree/default.nix
@@ -1,24 +1,52 @@
-{ lib, fetchFromGitHub, python2Packages, gettext }:
+{ stdenv
+, lib
+, fetchFromGitHub
+, cmake
+, pkg-config
+, python3
+, wrapGAppsHook
+, gtkmm3
+, gtksourceview
+, gtksourceviewmm
+, gspell
+, libxmlxx
+, sqlite
+, curl
+, libuchardet
+, fmt
+, spdlog
+}:
 
-python2Packages.buildPythonApplication rec {
+stdenv.mkDerivation rec {
   pname = "cherrytree";
-  version = "0.39.4";
+  version = "0.99.37";
 
   src = fetchFromGitHub {
     owner = "giuspen";
     repo = "cherrytree";
     rev = version;
-    sha256 = "1wycgn1f3b858qb6kn2bsaabak8n52qkpd24w54xz6fjizlnw7x0";
-
+    sha256 = "1a2scwjrjijxwyfpqih23zzay3yqhyzpxnp66388fcir1cmp8zih";
   };
 
-  nativeBuildInputs = [ gettext ];
+  nativeBuildInputs = [
+    cmake
+    pkg-config
+    python3
+    wrapGAppsHook
+  ];
 
-  propagatedBuildInputs = with python2Packages; [ pygtk dbus-python pygtksourceview ];
-
-  patches = [ ./subprocess.patch ];
-
-  doCheck = false;
+  buildInputs = [
+    gtkmm3
+    gtksourceview
+    gtksourceviewmm
+    gspell
+    libxmlxx
+    sqlite
+    curl
+    libuchardet
+    fmt
+    spdlog
+  ];
 
   meta = with lib; {
     description = "An hierarchical note taking application";
@@ -31,8 +59,9 @@ python2Packages.buildPythonApplication rec {
       you have scattered around your hard drive can be conveniently placed into
       a Cherrytree document where you can easily find it.
     '';
-    homepage = "http://www.giuspen.com/cherrytree";
-    license = licenses.gpl3;
+    homepage = "https://www.giuspen.com/cherrytree";
+    changelog = "https://raw.githubusercontent.com/giuspen/cherrytree/${version}/changelog.txt";
+    license = licenses.gpl3Plus;
     maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/applications/misc/cherrytree/subprocess.patch b/pkgs/applications/misc/cherrytree/subprocess.patch
deleted file mode 100644
index 1f80cde03b75..000000000000
--- a/pkgs/applications/misc/cherrytree/subprocess.patch
+++ /dev/null
@@ -1,14 +0,0 @@
-diff -Naur cherrytree-0.37.1-orig/setup.py cherrytree-0.37.1/setup.py
---- cherrytree-0.37.1-orig/setup.py	2016-01-08 20:50:50.000000000 +0100
-+++ cherrytree-0.37.1/setup.py	2016-07-05 20:30:27.768178682 +0200
-@@ -205,4 +205,9 @@
-           },
-        distclass=CherryTreeDist
-     )
--    subprocess.call("update-desktop-database")
-+    try:
-+        subprocess.check_call(['update-desktop-database'])
-+    except subprocess.CalledProcessError:
-+        pass # handle errors in the called executable
-+    except OSError:
-+        pass # executable not found
diff --git a/pkgs/development/libraries/gspell/0001-Darwin-build-fix.patch b/pkgs/development/libraries/gspell/0001-Darwin-build-fix.patch
new file mode 100644
index 000000000000..b2e71fe3aed1
--- /dev/null
+++ b/pkgs/development/libraries/gspell/0001-Darwin-build-fix.patch
@@ -0,0 +1,37 @@
+From 2d6dd1c286eb57fbf968510318cafc94888b98de Mon Sep 17 00:00:00 2001
+From: OPNA2608 <christoph.neidahl@gmail.com>
+Date: Sun, 13 Jun 2021 21:56:03 +0200
+Subject: [PATCH] Darwin build fix
+
+---
+ gspell/Makefile.am | 7 +++++++
+ 1 file changed, 7 insertions(+)
+
+diff --git a/gspell/Makefile.am b/gspell/Makefile.am
+index 69ee421..7c58973 100644
+--- a/gspell/Makefile.am
++++ b/gspell/Makefile.am
+@@ -95,6 +95,7 @@ nodist_libgspell_core_la_SOURCES = \
+ 	$(BUILT_SOURCES)
+ 
+ libgspell_core_la_LIBADD =	\
++	$(GTK_MAC_LIBS)           \
+ 	$(CODE_COVERAGE_LIBS)
+ 
+ libgspell_core_la_CFLAGS =			\
+@@ -161,6 +162,12 @@ gspell_private_headers += \
+ gspell_private_c_files += \
+ 	gspell-osx.c
+ 
++libgspell_core_la_CFLAGS += \
++	-xobjective-c
++
++libgspell_core_la_LDFLAGS += \
++	-framework Cocoa
++
+ endif # OS_OSX
+ 
+ if HAVE_INTROSPECTION
+-- 
+2.29.3
+
diff --git a/pkgs/development/libraries/gspell/default.nix b/pkgs/development/libraries/gspell/default.nix
index f591246eaf81..be45a48090ff 100644
--- a/pkgs/development/libraries/gspell/default.nix
+++ b/pkgs/development/libraries/gspell/default.nix
@@ -2,6 +2,8 @@
 , fetchurl
 , pkg-config
 , libxml2
+, autoreconfHook
+, gtk-doc
 , glib
 , gtk3
 , enchant2
@@ -9,6 +11,7 @@
 , vala
 , gobject-introspection
 , gnome
+, gtk-mac-integration
 }:
 
 stdenv.mkDerivation rec {
@@ -23,17 +26,26 @@ stdenv.mkDerivation rec {
     sha256 = "1pdb4gbjrs8mk6r0ipw5vxyvzav1wvkjq46kiq53r3nyznfpdfyw";
   };
 
+  patches = [
+    # Extracted from: https://github.com/Homebrew/homebrew-core/blob/2a27fb86b08afc7ae6dff79cf64aafb8ecc93275/Formula/gspell.rb#L125-L149
+    ./0001-Darwin-build-fix.patch
+  ];
+
   nativeBuildInputs = [
     pkg-config
     vala
     gobject-introspection
     libxml2
+    autoreconfHook
+    gtk-doc
   ];
 
   buildInputs = [
     glib
     gtk3
     icu
+  ] ++ lib.optionals stdenv.hostPlatform.isDarwin [
+    gtk-mac-integration
   ];
 
   propagatedBuildInputs = [
@@ -53,6 +65,6 @@ stdenv.mkDerivation rec {
     homepage = "https://wiki.gnome.org/Projects/gspell";
     license = licenses.lgpl21Plus;
     maintainers = teams.gnome.members;
-    platforms = platforms.linux;
+    platforms = platforms.unix;
   };
 }
diff --git a/pkgs/development/libraries/gtksourceviewmm/default.nix b/pkgs/development/libraries/gtksourceviewmm/default.nix
index fc4439e223ee..2b9124032590 100644
--- a/pkgs/development/libraries/gtksourceviewmm/default.nix
+++ b/pkgs/development/libraries/gtksourceviewmm/default.nix
@@ -20,7 +20,7 @@ stdenv.mkDerivation rec {
   buildInputs = [ glibmm gtkmm3 gtksourceview3 ];
 
   meta = with lib; {
-    platforms = platforms.linux;
+    platforms = platforms.unix;
     homepage = "https://developer.gnome.org/gtksourceviewmm/";
     description = "C++ wrapper for gtksourceview";
     license = licenses.lgpl2;