diff --git a/pkgs/by-name/es/esphome/esp32-post-build-esptool-reference.patch b/pkgs/by-name/es/esphome/esp32-post-build-esptool-reference.patch
new file mode 100644
index 000000000000..6f323145e85f
--- /dev/null
+++ b/pkgs/by-name/es/esphome/esp32-post-build-esptool-reference.patch
@@ -0,0 +1,13 @@
+diff --git a/esphome/components/esp32/post_build.py.script b/esphome/components/esp32/post_build.py.script
+index c99521423..e29821d7e 100644
+--- a/esphome/components/esp32/post_build.py.script
++++ b/esphome/components/esp32/post_build.py.script
+@@ -88,8 +88,6 @@ def merge_factory_bin(source, target, env):
+     output_path = firmware_path.with_suffix(".factory.bin")
+     python_exe = f'"{env.subst("$PYTHONEXE")}"'
+     cmd = [
+-        python_exe,
+-        "-m",
+         "esptool",
+         "--chip",
+         chip,
diff --git a/pkgs/by-name/es/esphome/package.nix b/pkgs/by-name/es/esphome/package.nix
index 8ddc1417ae04..fce4a85e7f8c 100644
--- a/pkgs/by-name/es/esphome/package.nix
+++ b/pkgs/by-name/es/esphome/package.nix
@@ -44,6 +44,14 @@ python.pkgs.buildPythonApplication rec {
     hash = "sha256-LOHsiSiqeCLrKLcVfAiPZl54aDTaYuKw073h0XMDiTE=";
   };
 
+  patches = [
+    # Use the esptool executable directly in the ESP32 post build script, that
+    # gets executed by platformio. This is required, because platformio uses its
+    # own python environment through `python -m esptool` and then fails to find
+    # the esptool library.
+    ./esp32-post-build-esptool-reference.patch
+  ];
+
   build-system = with python.pkgs; [
     setuptools
   ];