diff --git a/pkgs/development/libraries/libuv/default.nix b/pkgs/development/libraries/libuv/default.nix
index 495d760f0b61..47e29e4b1d1b 100644
--- a/pkgs/development/libraries/libuv/default.nix
+++ b/pkgs/development/libraries/libuv/default.nix
@@ -1,27 +1,18 @@
-{ stdenv, lib, fetchFromGitHub, fetchpatch, autoconf, automake, libtool, pkg-config, ApplicationServices, CoreServices, pkgsStatic }:
+{ stdenv, lib, fetchFromGitHub, autoconf, automake, libtool, pkg-config, ApplicationServices, CoreServices, pkgsStatic }:
 
 stdenv.mkDerivation rec {
-  version = "1.44.2";
+  version = "1.45.0";
   pname = "libuv";
 
   src = fetchFromGitHub {
     owner = pname;
     repo = pname;
     rev = "v${version}";
-    sha256 = "sha256-K6v+00basjI32ON27ZjC5spQi/zWCcslDwQwyosq2iY=";
+    sha256 = "sha256-qKw9QFR24Uw7pVA9isPH8Va+9/5DYuqXz6l6jWcXn+4=";
   };
 
   outputs = [ "out" "dev" ];
 
-  patches = [
-    # Fix tests for statically linked variant upstream PR is
-    # https://github.com/libuv/libuv/pull/3735
-    (fetchpatch {
-      url = "https://github.com/libuv/libuv/commit/9d898acc564351dde74e9ed9865144e5c41f5beb.patch";
-      sha256 = "sha256-6XsjrseD8a+ny887EKOX0NmHocLMXGf2YL13vkNHUZ0=";
-    })
-  ];
-
   postPatch = let
     toDisable = [
       "getnameinfo_basic" "udp_send_hang_loop" # probably network-dependent
@@ -30,7 +21,7 @@ stdenv.mkDerivation rec {
       "getaddrinfo_fail" "getaddrinfo_fail_sync"
       "threadpool_multiple_event_loops" # times out on slow machines
       "get_passwd" # passed on NixOS but failed on other Linuxes
-      "tcp_writealot" "udp_multicast_join" "udp_multicast_join6" # times out sometimes
+      "tcp_writealot" "udp_multicast_join" "udp_multicast_join6" "metrics_pool_events" # times out sometimes
       "fs_fstat" # https://github.com/libuv/libuv/issues/2235#issuecomment-1012086927
 
       # Assertion failed in test/test-tcp-bind6-error.c on line 60: r == UV_EADDRINUSE