diff --git a/pkgs/applications/terminal-emulators/lilyterm/default.nix b/pkgs/applications/terminal-emulators/lilyterm/default.nix
deleted file mode 100644
index 9e2d2a67b440..000000000000
--- a/pkgs/applications/terminal-emulators/lilyterm/default.nix
+++ /dev/null
@@ -1,58 +0,0 @@
-{ stdenv, lib, fetchurl, fetchFromGitHub
-, pkg-config
-, autoconf, automake, intltool, gettext
-, gtk, vte
-, flavour ? "stable"
-}:
-
-assert lib.assertOneOf "flavour" flavour [ "stable"  "git" ];
-
-let
-  pname = "lilyterm";
-  stuff =
-    if flavour == "stable"
-    then rec {
-        version = "0.9.9.4";
-        src = fetchurl {
-          url = "https://lilyterm.luna.com.tw/file/${pname}-${version}.tar.gz";
-          sha256 = "0x2x59qsxq6d6xg5sd5lxbsbwsdvkwqlk17iw3h4amjg3m1jc9mp";
-        };
-      }
-    else {
-        version = "2019-07-25";
-        src = fetchFromGitHub {
-          owner = "Tetralet";
-          repo = pname;
-          rev = "faf1254f46049edfb1fd6e9191e78b1b23b9c51d";
-          sha256 = "054450gk237c62b677365bcwrijr63gd9xm8pv68br371wdzylz7";
-        };
-      };
-
-in
-with lib;
-stdenv.mkDerivation rec {
-  inherit pname;
-
-  inherit (stuff) src version;
-
-  nativeBuildInputs = [ pkg-config autoconf automake intltool gettext ];
-  buildInputs = [ gtk vte ];
-
-  preConfigure = "sh autogen.sh";
-
-  configureFlags = [
-    "--enable-nls"
-    "--enable-safe-mode"
-  ];
-
-  meta = with lib; {
-    description = "A fast, lightweight terminal emulator";
-    longDescription = ''
-      LilyTerm is a terminal emulator based off of libvte that aims to be fast and lightweight.
-    '';
-    homepage = "https://lilyterm.luna.com.tw/";
-    license = licenses.gpl3;
-    maintainers = with maintainers; [ AndersonTorres Profpatsch ];
-    platforms = platforms.linux;
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 587a90b2aeb2..49c0c839bbc5 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -507,6 +507,8 @@ mapAliases ({
   libqmatrixclient = throw "libqmatrixclient was renamed to libquotient"; # added 2020-04-09
   libwnck3 = libwnck;
   lilypond-unstable = lilypond; # added 2021-03-11
+  lilyterm = throw "lilyterm has been removed from nixpkgs, because it was relying on a vte version that depended on python2."; # added 2022-01-14
+  lilyterm-git = throw "lilyterm-git has been removed from nixpkgs, because it was relying on a vte version that depended on python2."; # added 2022-01-14
   links = links2; # added 2016-01-31
   linuxband = throw "linuxband has been removed from nixpkgs, as it's abandoned upstream."; # added 2021-12-09
   linux_rpi0 = linuxKernel.kernels.linux_rpi1;
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 6f90fe1b9f40..8ae35111f443 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -1108,16 +1108,6 @@ with pkgs;
 
   lilo = callPackage ../tools/misc/lilo { };
 
-  lilyterm = callPackage ../applications/terminal-emulators/lilyterm {
-    inherit (gnome2) vte;
-    gtk = gtk2;
-    flavour = "stable";
-  };
-
-  lilyterm-git = lilyterm.override {
-    flavour = "git";
-  };
-
   logseq = callPackage ../applications/misc/logseq { };
 
   lxterminal = callPackage ../applications/terminal-emulators/lxterminal { };