diff --git a/pkgs/development/python-modules/magic-wormhole/default.nix b/pkgs/development/python-modules/magic-wormhole/default.nix
index 528b71063274..90fc7a9a2cbd 100644
--- a/pkgs/development/python-modules/magic-wormhole/default.nix
+++ b/pkgs/development/python-modules/magic-wormhole/default.nix
@@ -44,20 +44,32 @@ buildPythonPackage rec {
     hash = "sha256-AG0jn4i/98N7wu/2CgBOJj+vklj3J5GS0Gugyc7WsIA=";
   };
 
-  nativeBuildInputs = [ setuptools ];
+  postPatch =
+    # enable tests by fixing the location of the wormhole binary
+    ''
+      substituteInPlace src/wormhole/test/test_cli.py --replace-fail \
+        'locations = procutils.which("wormhole")' \
+        'return "${placeholder "out"}/bin/wormhole"'
+    ''
+    # fix the location of the ifconfig binary
+    + lib.optionalString stdenv.isLinux ''
+      sed -i -e "s|'ifconfig'|'${nettools}/bin/ifconfig'|" src/wormhole/ipaddrs.py
+    '';
 
-  propagatedBuildInputs = [
-    spake2
-    pynacl
-    six
+  build-system = [ setuptools ];
+
+  dependencies = [
     attrs
-    twisted
     autobahn
     automat
-    tqdm
     click
     humanize
     iterable-io
+    pynacl
+    six
+    spake2
+    tqdm
+    twisted
     txtorcon
     zipstream-ng
   ] ++ autobahn.optional-dependencies.twisted ++ twisted.optional-dependencies.tls;
@@ -66,43 +78,33 @@ buildPythonPackage rec {
     dilation = [ noiseprotocol ];
   };
 
-  nativeCheckInputs = [
-    mock
-    magic-wormhole-transit-relay
-    magic-wormhole-mailbox-server
-    pytestCheckHook
-  ] ++ passthru.optional-dependencies.dilation ++ lib.optionals stdenv.isDarwin [ unixtools.locale ];
+  nativeCheckInputs =
+    # For Python 3.12, remove magic-wormhole-mailbox-server and magic-wormhole-transit-relay from test dependencies,
+    # which are not yet supported with this version.
+    lib.optionals (!magic-wormhole-mailbox-server.meta.broken) [ magic-wormhole-mailbox-server ]
+    ++ lib.optionals (!magic-wormhole-transit-relay.meta.broken) [ magic-wormhole-transit-relay ]
+    ++ [
+      mock
+      pytestCheckHook
+    ]
+    ++ passthru.optional-dependencies.dilation
+    ++ lib.optionals stdenv.isDarwin [ unixtools.locale ];
 
-  disabledTests = lib.optionals stdenv.isDarwin [
-    # These tests doesn't work within Darwin's sandbox
-    "test_version"
-    "test_text"
-    "test_receiver"
-    "test_sender"
-    "test_sender_allocation"
-    "test_text_wrong_password"
-    "test_override"
-    "test_allocate_port"
-    "test_allocate_port_no_reuseaddr"
-    "test_ignore_localhost_hint"
-    "test_ignore_localhost_hint_orig"
-    "test_keep_only_localhost_hint"
-    "test_get_direct_hints"
-    "test_listener"
-    "test_success_direct"
-    "test_direct"
-    "test_relay"
-  ];
+  __darwinAllowLocalNetworking = true;
 
-  disabledTestPaths = lib.optionals stdenv.isDarwin [
-    # These tests doesn't work within Darwin's sandbox
-    "src/wormhole/test/test_xfer_util.py"
-    "src/wormhole/test/test_wormhole.py"
-  ];
-
-  postPatch = lib.optionalString stdenv.isLinux ''
-    sed -i -e "s|'ifconfig'|'${nettools}/bin/ifconfig'|" src/wormhole/ipaddrs.py
-  '';
+  disabledTestPaths =
+    # For Python 3.12, remove the tests depending on magic-wormhole-mailbox-server and magic-wormhole-transit-relay,
+    # which are not yet supported with this version.
+    lib.optionals
+      (magic-wormhole-mailbox-server.meta.broken || magic-wormhole-transit-relay.meta.broken)
+      [
+        "src/wormhole/test/dilate/test_full.py"
+        "src/wormhole/test/test_args.py"
+        "src/wormhole/test/test_cli.py"
+        "src/wormhole/test/test_wormhole.py"
+        "src/wormhole/test/test_xfer_util.py"
+      ]
+    ++ lib.optionals magic-wormhole-transit-relay.meta.broken [ "src/wormhole/test/test_transit.py" ];
 
   postInstall = ''
     install -Dm644 docs/wormhole.1 $out/share/man/man1/wormhole.1