diff --git a/pkgs/applications/audio/sublime-music/default.nix b/pkgs/applications/audio/sublime-music/default.nix
index 3f7e1e038f8e..4b50ff3e7ea0 100644
--- a/pkgs/applications/audio/sublime-music/default.nix
+++ b/pkgs/applications/audio/sublime-music/default.nix
@@ -28,9 +28,14 @@ python3Packages.buildPythonApplication rec {
   nativeBuildInputs = [
     gobject-introspection
     python3Packages.poetry-core
+    python3Packages.pythonRelaxDepsHook
     wrapGAppsHook
   ];
 
+  # Can be removed in later versions
+  # https://gitlab.com/sublime-music/sublime-music/-/issues/343
+  pythonRelaxDeps = [ "python-mpv" ];
+
   buildInputs = [
     gtk3
     pango
diff --git a/pkgs/applications/graphics/hydrus/default.nix b/pkgs/applications/graphics/hydrus/default.nix
index 6b991e8dd398..4b421b41d9a3 100644
--- a/pkgs/applications/graphics/hydrus/default.nix
+++ b/pkgs/applications/graphics/hydrus/default.nix
@@ -10,14 +10,14 @@
 
 python3Packages.buildPythonPackage rec {
   pname = "hydrus";
-  version = "497";
+  version = "500";
   format = "other";
 
   src = fetchFromGitHub {
     owner = "hydrusnetwork";
     repo = "hydrus";
     rev = "refs/tags/v${version}";
-    sha256 = "sha256-dQ6a3jys6V1ihT6q8FUaX7jOA1ZDZdX5EUy03ILk7vM=";
+    sha256 = "sha256-gsOto37++++ucpDC0ri3HhROp7v6qlHENjFvsbuyM6k=";
   };
 
   nativeBuildInputs = [
@@ -33,7 +33,6 @@ python3Packages.buildPythonPackage rec {
     html5lib
     lxml
     lz4
-    nose
     numpy
     opencv4
     pillow
diff --git a/pkgs/development/python-modules/mpv/default.nix b/pkgs/development/python-modules/mpv/default.nix
index 11d0bed476af..01d9d58b23db 100644
--- a/pkgs/development/python-modules/mpv/default.nix
+++ b/pkgs/development/python-modules/mpv/default.nix
@@ -4,14 +4,14 @@
 
 buildPythonPackage rec {
   pname = "mpv";
-  version = "0.5.2";
+  version = "1.0.1";
   disabled = isPy27;
 
   src = fetchFromGitHub {
     owner = "jaseg";
     repo = "python-mpv";
     rev = "v${version}";
-    sha256 = "0ffskpynhl1252h6a05087lvpjgn1cn2z3caiv3i666dn1n79fjd";
+    sha256 = "sha256-UCJ1PknnWQiFciTEMxTUqDzz0Z8HEWycLuQqYeyQhoM=";
   };
 
   buildInputs = [ mpv ];