diff --git a/pkgs/development/libraries/libpsl/default.nix b/pkgs/development/libraries/libpsl/default.nix
index 1659a55cb4ef..e41369db79f5 100644
--- a/pkgs/development/libraries/libpsl/default.nix
+++ b/pkgs/development/libraries/libpsl/default.nix
@@ -41,7 +41,9 @@ stdenv.mkDerivation rec {
     libidn2
     libunistring
     libxslt
-  ] ++ lib.optional (!stdenv.hostPlatform.isStatic) python3;
+  ] ++ lib.optional (
+    !stdenv.hostPlatform.isStatic && (stdenv.hostPlatform.isDarwin -> stdenv.buildPlatform == stdenv.hostPlatform)
+  ) python3;
 
   propagatedBuildInputs = [
     publicsuffix-list