diff --git a/pkgs/applications/office/qnotero/default.nix b/pkgs/applications/office/qnotero/default.nix
index e90184b52212..ff7ce4121298 100644
--- a/pkgs/applications/office/qnotero/default.nix
+++ b/pkgs/applications/office/qnotero/default.nix
@@ -1,4 +1,4 @@
-{ lib, fetchFromGitHub, python3Packages, wrapQtAppsHook }:
+{ lib, stdenv, fetchFromGitHub, python3Packages, wrapQtAppsHook }:
 
 python3Packages.buildPythonPackage rec {
   pname = "qnotero";
@@ -46,6 +46,7 @@ python3Packages.buildPythonPackage rec {
     homepage = "https://www.cogsci.nl/software/qnotero";
     license = lib.licenses.gpl2;
     platforms = lib.platforms.unix;
+    broken = stdenv.isDarwin; # Build fails even after adding cx-freeze to `buildInputs`
     maintainers = [ lib.maintainers.nico202 ];
   };
 }
diff --git a/pkgs/tools/networking/persepolis/default.nix b/pkgs/tools/networking/persepolis/default.nix
index ed449ecb992f..a4ba2b4f04aa 100644
--- a/pkgs/tools/networking/persepolis/default.nix
+++ b/pkgs/tools/networking/persepolis/default.nix
@@ -1,4 +1,4 @@
-{ lib, buildPythonApplication, fetchFromGitHub
+{ lib, stdenv, buildPythonApplication, fetchFromGitHub
 , aria
 , libnotify
 , pulseaudio
@@ -64,6 +64,7 @@ buildPythonApplication rec {
   meta = with lib; {
     description = "Persepolis Download Manager is a GUI for aria2";
     homepage = "https://persepolisdm.github.io/";
+    broken = stdenv.isDarwin; # Upstream’s build scripts check and fail on Darwin.
     license = licenses.gpl3;
     maintainers = [ ];
   };