diff --git a/pkgs/os-specific/darwin/apple-source-releases/libffi/package.nix b/pkgs/os-specific/darwin/apple-source-releases/libffi/package.nix
index 4fe40e86aab9..942f0a26da43 100644
--- a/pkgs/os-specific/darwin/apple-source-releases/libffi/package.nix
+++ b/pkgs/os-specific/darwin/apple-source-releases/libffi/package.nix
@@ -27,6 +27,8 @@ mkAppleDerivation (finalAttrs: {
     ./patches/llvm-18-compatibility.patch
     # Fix a memory leak when using the trampoline dylib. See https://github.com/libffi/libffi/pull/621#discussion_r955298301.
     ./patches/fix-tramponline-memory-leak.patch
+    # Fix automake-18.18 compatibility, https://github.com/libffi/libffi/issues/853#issuecomment-2909994482
+    ./patches/automake-1.18.patch
   ];
 
   # Make sure libffi is using the trampolines dylib in this package not the system one.
diff --git a/pkgs/os-specific/darwin/apple-source-releases/libffi/patches/automake-1.18.patch b/pkgs/os-specific/darwin/apple-source-releases/libffi/patches/automake-1.18.patch
new file mode 100644
index 000000000000..148baa6d1e86
--- /dev/null
+++ b/pkgs/os-specific/darwin/apple-source-releases/libffi/patches/automake-1.18.patch
@@ -0,0 +1,14 @@
+The hunk is used from https://github.com/libffi/libffi/issues/853#issuecomment-2909994482
+--- a/Makefile.am
++++ b/Makefile.am
+@@ -4,6 +4,10 @@ AUTOMAKE_OPTIONS = foreign subdir-objects
+ 
+ ACLOCAL_AMFLAGS = -I m4
+ 
++# Alias required by AX_ENABLE_BUILDDIR / config-ml
++.PHONY: all-configured
++all-configured: all
++
+ SUBDIRS = include testsuite man
+ if BUILD_DOCS
+ ## This hack is needed because it doesn't seem possible to make a