diff --git a/pkgs/by-name/ld/ld64/package.nix b/pkgs/by-name/ld/ld64/package.nix
index ee773bacf3a5..2b00fdfb62db 100644
--- a/pkgs/by-name/ld/ld64/package.nix
+++ b/pkgs/by-name/ld/ld64/package.nix
@@ -170,7 +170,9 @@ stdenv.mkDerivation (finalAttrs: {
     cd "$NIX_BUILD_TOP/$sourceRoot"
 
     export NIX_CFLAGS_COMPILE+=" --ld-path=$out/bin/${targetPrefix}ld"
-    meson setup build-install-check -Db_lto=true --buildtype=$mesonBuildType
+    meson setup build-install-check -Db_lto=true --buildtype=$mesonBuildType${
+      lib.optionalString (targetPrefix != "") " -Dtarget_prefix=${targetPrefix}"
+    }
 
     cd build-install-check
     ninja ${targetPrefix}ld "-j$NIX_BUILD_CORES"