diff --git a/pkgs/applications/misc/fme/default.nix b/pkgs/applications/misc/fme/default.nix
deleted file mode 100644
index 03a9f875a793..000000000000
--- a/pkgs/applications/misc/fme/default.nix
+++ /dev/null
@@ -1,59 +0,0 @@
-{ lib
-, stdenv
-, fetchFromGitHub
-, autoconf
-, automake
-, bc
-, fluxbox
-, gettext
-, glibmm
-, gtkmm2
-, libglademm
-, libsigcxx
-, pkg-config
-}:
-
-stdenv.mkDerivation rec {
-  pname = "fme";
-  version = "1.1.3";
-
-  src = fetchFromGitHub {
-    owner = "rdehouss";
-    repo = "fme";
-    rev = "v${version}";
-    sha256 = "sha256-P67OmExBdWM6NZhDyYceVJOZiy8RC+njk/QvgQcWZeQ=";
-  };
-
-  nativeBuildInputs = [
-    autoconf
-    automake
-    gettext
-    pkg-config
-  ];
-  buildInputs = [
-    bc
-    fluxbox
-    glibmm
-    gtkmm2
-    libglademm
-    libsigcxx
-  ];
-
-  preConfigure = ''
-    ./autogen.sh
-  '';
-
-  meta = with lib; {
-    homepage = "https://github.com/rdehouss/fme/";
-    description = "Editor for Fluxbox menus";
-    longDescription = ''
-      Fluxbox Menu Editor is a menu editor for the Window Manager Fluxbox
-      written in C++ with the libraries Gtkmm, Glibmm, libglademm and gettext
-      for internationalization.  Its user-friendly interface will help you to
-      edit, delete, move (Drag and Drop) a row, a submenu, etc very easily.
-    '';
-    license = licenses.gpl2Plus;
-    maintainers = [ maintainers.AndersonTorres ];
-    platforms = platforms.linux;
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 060f2c068750..2c33cff14a08 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -284,6 +284,7 @@ mapAliases ({
   flutter-beta = throw "Non-stable versions of Flutter have been removed. You can use flutterPackages.mkFlutter to generate a package for other Flutter versions."; # added 2020-01-15
   flutter-dev = throw "Non-stable versions of Flutter have been removed. You can use flutterPackages.mkFlutter to generate a package for other Flutter versions."; # added 2020-01-15
   flvtool2 = throw "flvtool2 has been removed."; # added 2020-11-03
+  fme = throw "fme was removed, because it is old and uses Glade, a discontinued library."; # added 2022-01-26
   foldingathome = fahclient; # added 2020-09-03
   font-awesome-ttf = font-awesome; # 2018-02-25
   # 2019-10-31
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index cfc6390f5f7a..778ce279d7e6 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -25737,10 +25737,6 @@ with pkgs;
 
   fluxbox = callPackage ../applications/window-managers/fluxbox { };
 
-  fme = callPackage ../applications/misc/fme {
-    inherit (gnome2) libglademm;
-  };
-
   fomp = callPackage ../applications/audio/fomp { };
 
   formatter = callPackage ../applications/misc/formatter { };