diff --git a/pkgs/development/libraries/openssl/default.nix b/pkgs/development/libraries/openssl/default.nix
index 7c702660d390..bb9eb51123d2 100644
--- a/pkgs/development/libraries/openssl/default.nix
+++ b/pkgs/development/libraries/openssl/default.nix
@@ -186,11 +186,6 @@ let
             "--openssldir=/.$(etc)/etc/ssl"
         )
       ]
-      # Tell build system it's cross environment. This allows to skip tests
-      # that would fail when libc is different. Otherwise, run the tests.
-      ++ lib.optional (
-        !lib.systems.equals stdenv.buildPlatform stdenv.hostPlatform
-      ) "--cross-compile-prefix=${lib.getBin stdenv.cc}/bin/"
       ++ lib.optionals withCryptodev [
         "-DHAVE_CRYPTODEV"
         "-DUSE_CRYPTODEV_DIGESTS"