diff --git a/pkgs/development/python-modules/marshmallow/default.nix b/pkgs/development/python-modules/marshmallow/default.nix
index 4b67ac402089..0ab9cf7f5dab 100644
--- a/pkgs/development/python-modules/marshmallow/default.nix
+++ b/pkgs/development/python-modules/marshmallow/default.nix
@@ -1,5 +1,6 @@
 {
   lib,
+  stdenv,
   buildPythonPackage,
   fetchFromGitHub,
   flit-core,
@@ -29,6 +30,11 @@ buildPythonPackage rec {
     simplejson
   ];
 
+  disabledTests = lib.optionals stdenv.hostPlatform.isx86_32 [
+    # Raises a slightly different error than upstream expects: 'Timestamp is too large' instead of 'out of range'
+    "test_from_timestamp_with_overflow_value"
+  ];
+
   pythonImportsCheck = [ "marshmallow" ];
 
   meta = with lib; {