diff --git a/maintainers/scripts/bootstrap-files/refresh-tarballs.bash b/maintainers/scripts/bootstrap-files/refresh-tarballs.bash
index eb4aa1667cd7..87731089a9dd 100755
--- a/maintainers/scripts/bootstrap-files/refresh-tarballs.bash
+++ b/maintainers/scripts/bootstrap-files/refresh-tarballs.bash
@@ -95,6 +95,7 @@ CROSS_TARGETS=(
     powerpc64-unknown-linux-gnuabielfv2
     powerpc64le-unknown-linux-gnu
     riscv64-unknown-linux-gnu
+    s390x-unknown-linux-gnu
     x86_64-unknown-freebsd
 )
 
diff --git a/pkgs/build-support/bintools-wrapper/default.nix b/pkgs/build-support/bintools-wrapper/default.nix
index 215dd0f39cd7..7fe0762090c5 100644
--- a/pkgs/build-support/bintools-wrapper/default.nix
+++ b/pkgs/build-support/bintools-wrapper/default.nix
@@ -120,6 +120,7 @@ let
     else if targetPlatform.libc == "nblibc"           then "${sharedLibraryLoader}/libexec/ld.elf_so"
     else if targetPlatform.system == "i686-linux"     then "${sharedLibraryLoader}/lib/ld-linux.so.2"
     else if targetPlatform.system == "x86_64-linux"   then "${sharedLibraryLoader}/lib/ld-linux-x86-64.so.2"
+    else if targetPlatform.system == "s390x-linux"    then "${sharedLibraryLoader}/lib/ld64.so.1"
     # ELFv1 (.1) or ELFv2 (.2) ABI
     else if targetPlatform.isPower64                  then "${sharedLibraryLoader}/lib/ld64.so.*"
     # ARM with a wildcard, which can be "" or "-armhf".
diff --git a/pkgs/stdenv/linux/bootstrap-files/s390x-unknown-linux-gnu.nix b/pkgs/stdenv/linux/bootstrap-files/s390x-unknown-linux-gnu.nix
new file mode 100644
index 000000000000..6c9501b33257
--- /dev/null
+++ b/pkgs/stdenv/linux/bootstrap-files/s390x-unknown-linux-gnu.nix
@@ -0,0 +1,21 @@
+# Autogenerated by maintainers/scripts/bootstrap-files/refresh-tarballs.bash as:
+# $ ./refresh-tarballs.bash --targets=s390x-unknown-linux-gnu
+#
+# Metadata:
+# - nixpkgs revision: 8ba481d65eb21a4f9e6b1e812de3f83079eb8016
+# - hydra build: https://hydra.nixos.org/job/nixpkgs/cross-trunk/bootstrapTools.s390x-unknown-linux-gnu.build/latest
+# - resolved hydra build: https://hydra.nixos.org/build/267960435
+# - instantiated derivation: /nix/store/hqmllvbilxslp393ci4lkj66psh5iv6a-stdenv-bootstrap-tools-s390x-unknown-linux-gnu.drv
+# - output directory: /nix/store/wnr3zf16ci8ajxnv0v6w3dn8lm93gp5z-stdenv-bootstrap-tools-s390x-unknown-linux-gnu
+# - build time: Sun, 28 Jul 2024 14:47:36 +0000
+{
+  bootstrapTools = import <nix/fetchurl.nix> {
+    url = "http://tarballs.nixos.org/stdenv/s390x-unknown-linux-gnu/8ba481d65eb21a4f9e6b1e812de3f83079eb8016/bootstrap-tools.tar.xz";
+    hash = "sha256-fuKIRXznA8hU8uGpxldAUNvuJBZ/xiyJUByNbpBCaH8=";
+  };
+  busybox = import <nix/fetchurl.nix> {
+    url = "http://tarballs.nixos.org/stdenv/s390x-unknown-linux-gnu/8ba481d65eb21a4f9e6b1e812de3f83079eb8016/busybox";
+    hash = "sha256-R6nAiaIOgShKiu+qcOP9apVpnuJgTAGAsJxWSHsH4/A=";
+    executable = true;
+  };
+}
diff --git a/pkgs/stdenv/linux/default.nix b/pkgs/stdenv/linux/default.nix
index 1f1c4771d167..a81ccfeb1188 100644
--- a/pkgs/stdenv/linux/default.nix
+++ b/pkgs/stdenv/linux/default.nix
@@ -73,6 +73,7 @@
       powerpc64-linux = import ./bootstrap-files/powerpc64-unknown-linux-gnuabielfv2.nix;
       powerpc64le-linux = import ./bootstrap-files/powerpc64le-unknown-linux-gnu.nix;
       riscv64-linux = import ./bootstrap-files/riscv64-unknown-linux-gnu.nix;
+      s390x-linux = import ./bootstrap-files/s390x-unknown-linux-gnu.nix;
     };
     musl = {
       aarch64-linux = import ./bootstrap-files/aarch64-unknown-linux-musl.nix;