diff --git a/pkgs/development/python-modules/twisted/default.nix b/pkgs/development/python-modules/twisted/default.nix
index e78d06eb7bac..ea7cca173a17 100644
--- a/pkgs/development/python-modules/twisted/default.nix
+++ b/pkgs/development/python-modules/twisted/default.nix
@@ -1,5 +1,6 @@
 { lib, stdenv
 , buildPythonPackage
+, fetchpatch
 , fetchPypi
 , python
 , zope_interface
@@ -25,6 +26,18 @@ buildPythonPackage rec {
     sha256 = "1wml02jxni8k15984pskks7d6yin81w4d2ac026cpyiqd0gjpwsp";
   };
 
+  patches = [
+    (fetchpatch {
+      # https://github.com/twisted/twisted/security/advisories/GHSA-c2jg-hw38-jrqq
+      name = "CVE-2022-24801.patch";
+      url = "https://github.com/twisted/twisted/commit/592217e951363d60e9cd99c5bbfd23d4615043ac.patch";
+      hash = "sha256-psX5vAM9myuILuTazpebSk8QTT52CB6N7RXAY4MAV8g=";
+      excludes = [
+        "src/twisted/web/newsfragments/10323.bugfix"
+      ];
+    })
+  ];
+
   propagatedBuildInputs = [ zope_interface incremental automat constantly hyperlink pyhamcrest attrs setuptools typing-extensions ];
 
   passthru.extras.tls = [ pyopenssl service-identity idna ];