diff --git a/pkgs/development/compilers/ocaml/generic.nix b/pkgs/development/compilers/ocaml/generic.nix
index b0398fdc39cb..7a85f303fd06 100644
--- a/pkgs/development/compilers/ocaml/generic.nix
+++ b/pkgs/development/compilers/ocaml/generic.nix
@@ -49,7 +49,7 @@ let
 in
 
 let
-  useNativeCompilers = !stdenv.hostPlatform.isMips;
+  useNativeCompilers = !stdenv.hostPlatform.isMips && !stdenv.hostPlatform.isLoongArch64;
   inherit (lib)
     optional
     optionals