diff --git a/pkgs/development/compilers/gcc/common/configure-flags.nix b/pkgs/development/compilers/gcc/common/configure-flags.nix
index a60a3380ea25..7d59eee55f25 100644
--- a/pkgs/development/compilers/gcc/common/configure-flags.nix
+++ b/pkgs/development/compilers/gcc/common/configure-flags.nix
@@ -244,6 +244,11 @@ let
     ++ lib.optionals (langD) [
       "--with-target-system-zlib=yes"
     ]
+    # On mips64-unknown-linux-gnu libsanitizer defines collide with
+    # glibc's definitions and fail the build. It was fixed in gcc-13+.
+    ++ lib.optionals (targetPlatform.isMips && targetPlatform.parsed.abi.name == "gnu" && lib.versions.major version == "12") [
+      "--disable-libsanitizer"
+    ]
   ;
 
 in configureFlags