diff --git a/pkgs/development/interpreters/python/wrap-python.nix b/pkgs/development/interpreters/python/wrap-python.nix
index 1efd777bb052..4ff0a62d7fbd 100644
--- a/pkgs/development/interpreters/python/wrap-python.nix
+++ b/pkgs/development/interpreters/python/wrap-python.nix
@@ -7,7 +7,7 @@ with lib;
 
 makeSetupHook {
       deps = makeWrapper;
-      substitutions.libPrefix = python.libPrefix;
+      substitutions.sitePackages = python.sitePackages;
       substitutions.executable = python.interpreter;
       substitutions.python = python;
       substitutions.magicalSedExpression = let
diff --git a/pkgs/development/interpreters/python/wrap.sh b/pkgs/development/interpreters/python/wrap.sh
index 01b573e6ad5d..6fa8c316a17d 100644
--- a/pkgs/development/interpreters/python/wrap.sh
+++ b/pkgs/development/interpreters/python/wrap.sh
@@ -92,7 +92,7 @@ _addToPythonPath() {
     pythonPathsSeen[$dir]=1
     # addToSearchPath is defined in stdenv/generic/setup.sh. It will have
     # the effect of calling `export program_X=$dir/...:$program_X`.
-    addToSearchPath program_PYTHONPATH $dir/lib/@libPrefix@/site-packages
+    addToSearchPath program_PYTHONPATH $dir/@sitePackages@
     addToSearchPath program_PATH $dir/bin
 
     # Inspect the propagated inputs (if they exist) and recur on them.
@@ -113,9 +113,9 @@ createBuildInputsPth() {
             if $(echo -n $x |grep -q python-recursive-pth-loader); then
                 continue
             fi
-            if test -d "$x"/lib/@libPrefix@/site-packages; then
-                echo $x/lib/@libPrefix@/site-packages \
-                    >> "$out"/lib/@libPrefix@/site-packages/${name}-nix-python-$category.pth
+            if test -d "$x"/@sitePackages@; then
+                echo $x/@sitePackages@ \
+                    >> "$out"/@sitePackages@/${name}-nix-python-$category.pth
             fi
         done
     fi