diff --git a/pkgs/development/compilers/mono/4.nix b/pkgs/development/compilers/mono/4.nix
index 02c6177c9df0..0b283d4f1778 100644
--- a/pkgs/development/compilers/mono/4.nix
+++ b/pkgs/development/compilers/mono/4.nix
@@ -1,9 +1,9 @@
-{ callPackage, Foundation, libobjc }:
+{ callPackage, Foundation, libobjc, stdenv, lib }:
 
 callPackage ./generic.nix ({
   inherit Foundation libobjc;
   version = "4.8.1.0";
   sha256 = "1vyvp2g28ihcgxgxr8nhzyzdmzicsh5djzk8dk1hj5p5f2k3ijqq";
   enableParallelBuilding = false; # #32386, https://hydra.nixos.org/build/65600645
-  extraPatches = [ ./mono4-glibc.patch ];
+  extraPatches = lib.optionals stdenv.isLinux [ ./mono4-glibc.patch ];
 })
diff --git a/pkgs/development/compilers/mono/generic.nix b/pkgs/development/compilers/mono/generic.nix
index 7083945e73ab..e79a06cae7f5 100644
--- a/pkgs/development/compilers/mono/generic.nix
+++ b/pkgs/development/compilers/mono/generic.nix
@@ -76,7 +76,9 @@ stdenv.mkDerivation rec {
   inherit enableParallelBuilding;
 
   meta = with lib; {
-    broken = stdenv.isDarwin;
+    # Per nixpkgs#151720 the build failures for aarch64-darwin are fixed upstream, but a
+    # stable release with the fix is not available yet.
+    broken = stdenv.isDarwin && stdenv.isAarch64 && lib.versionOlder version "6.12.0.129";
     homepage = "https://mono-project.com/";
     description = "Cross platform, open source .NET development framework";
     platforms = with platforms; darwin ++ linux;