diff --git a/pkgs/development/python-modules/pynacl/default.nix b/pkgs/development/python-modules/pynacl/default.nix
index cc610d62e388..5f5b26a17acb 100644
--- a/pkgs/development/python-modules/pynacl/default.nix
+++ b/pkgs/development/python-modules/pynacl/default.nix
@@ -2,6 +2,7 @@
   lib,
   buildPythonPackage,
   fetchPypi,
+  fetchpatch2,
   pytestCheckHook,
   sphinxHook,
   pythonOlder,
@@ -27,6 +28,14 @@ buildPythonPackage rec {
     sha256 = "8ac7448f09ab85811607bdd21ec2464495ac8b7c66d146bf545b0f08fb9220ba";
   };
 
+  patches = [
+    (fetchpatch2 {
+      # sphinx 8 compat
+      url = "https://github.com/pyca/pynacl/commit/81943b3c61b9cc731ae0f2e87b7a91e42fbc8fa1.patch";
+      hash = "sha256-iO3pBqGW2zZE8lG8khpPjqJso9/rmFbdnwCcBs8iFeI=";
+    })
+  ];
+
   nativeBuildInputs = [ sphinxHook ];
 
   buildInputs = [ libsodium ];