diff --git a/pkgs/development/python-modules/blessed/default.nix b/pkgs/development/python-modules/blessed/default.nix
index 659f3523d5b3..82c357dfdb8a 100644
--- a/pkgs/development/python-modules/blessed/default.nix
+++ b/pkgs/development/python-modules/blessed/default.nix
@@ -1,5 +1,6 @@
 {
   lib,
+  stdenv,
   buildPythonPackage,
   fetchFromGitHub,
   flit-core,
@@ -41,6 +42,11 @@ buildPythonPackage {
     rm tox.ini
   '';
 
+  disabledTestPaths = lib.optionals stdenv.hostPlatform.isDarwin [
+    # Fail with several AssertionError
+    "tests/test_sixel.py"
+  ];
+
   meta = {
     homepage = "https://github.com/jquast/blessed";
     description = "Thin, practical wrapper around terminal capabilities in Python";