diff --git a/pkgs/development/python-modules/pycryptodome/default.nix b/pkgs/development/python-modules/pycryptodome/default.nix
index 29ef48bde165..41d7dc1d1514 100644
--- a/pkgs/development/python-modules/pycryptodome/default.nix
+++ b/pkgs/development/python-modules/pycryptodome/default.nix
@@ -2,7 +2,6 @@
 , buildPythonPackage
 , callPackage
 , fetchFromGitHub
-, cffi
 , gmp
 }:
 
@@ -11,14 +10,14 @@ let
 in
 buildPythonPackage rec {
   pname = "pycryptodome";
-  version = "3.15.0";
+  version = "3.16.0";
   format = "setuptools";
 
   src = fetchFromGitHub {
     owner = "Legrandin";
     repo = "pycryptodome";
     rev = "v${version}";
-    hash = "sha256-SPRoAfwP1MFlVzZsVWmXDWUY5Yje7eg7d+9zJhZNXrw=";
+    hash = "sha256-8EAgeAU3HQiPrMKOtoVQQLbgq47cbveU2eQYp15XS/U=";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/pycryptodome/vectors.nix b/pkgs/development/python-modules/pycryptodome/vectors.nix
index f6a2b715ad91..89df4507867e 100644
--- a/pkgs/development/python-modules/pycryptodome/vectors.nix
+++ b/pkgs/development/python-modules/pycryptodome/vectors.nix
@@ -5,12 +5,12 @@
 
 buildPythonPackage rec {
   pname = "pycryptodome-test-vectors";
-  version = "1.0.8";
+  version = "1.0.10";
   format = "setuptools";
 
   src = fetchPypi {
     inherit pname version;
-    hash = "sha256-3BTh7as4CikvVfUx2xBZlUOaq/dAQNNFHpuRxWg/5N0=";
+    hash = "sha256-oqgHWAw0Xrc22eAuY6+Q/H90tL9Acz6V0EJp060hH2Q=";
     extension = "zip";
   };