diff --git a/pkgs/development/libraries/science/chemistry/cppe/default.nix b/pkgs/development/libraries/science/chemistry/cppe/default.nix
index 51083e5a2ae9..9781ce780660 100644
--- a/pkgs/development/libraries/science/chemistry/cppe/default.nix
+++ b/pkgs/development/libraries/science/chemistry/cppe/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, lib, fetchFromGitHub, cmake }:
+{ stdenv, lib, fetchFromGitHub, cmake, llvmPackages }:
 
 stdenv.mkDerivation rec {
   pname = "cppe";
@@ -11,7 +11,8 @@ stdenv.mkDerivation rec {
     sha256 = "sha256-guM7+ZWDJLcAUJtPkKLvC4LYSA2eBvER7cgwPZ7FxHw=";
   };
 
-  nativeBuildInputs = [ cmake ];
+  nativeBuildInputs = [ cmake ]
+    ++ lib.optionals stdenv.cc.isClang [ llvmPackages.openmp ];
 
   cmakeFlags = [ "-DCMAKE_INSTALL_LIBDIR=lib" ];
 
diff --git a/pkgs/development/python-modules/cppe/default.nix b/pkgs/development/python-modules/cppe/default.nix
index df00bd8dd120..52031bab74f7 100644
--- a/pkgs/development/python-modules/cppe/default.nix
+++ b/pkgs/development/python-modules/cppe/default.nix
@@ -1,5 +1,6 @@
 { buildPythonPackage
 , lib
+, stdenv
 , cmake
 , cppe
 , eigen
@@ -12,6 +13,7 @@
 , pandas
 , polarizationsolver
 , pytest
+, llvmPackages
 }:
 
 buildPythonPackage rec {
@@ -31,7 +33,12 @@ buildPythonPackage rec {
 
   dontUseCmakeConfigure = true;
 
-  buildInputs = [ pybind11 ];
+  buildInputs = [ pybind11 ]
+    ++ lib.optional stdenv.cc.isClang llvmPackages.openmp;
+
+  NIX_CFLAGS_LINK = lib.optional stdenv.cc.isClang "-lomp";
+
+  hardeningDisable = lib.optional stdenv.cc.isClang "strictoverflow";
 
   checkInputs = [
     pytest