diff --git a/pkgs/by-name/ht/htslib/package.nix b/pkgs/by-name/ht/htslib/package.nix
index c65baa3ff342..fdb42b4f3c14 100644
--- a/pkgs/by-name/ht/htslib/package.nix
+++ b/pkgs/by-name/ht/htslib/package.nix
@@ -7,6 +7,7 @@
   bzip2,
   xz,
   curl,
+  libdeflate,
   perl,
 }:
 
@@ -34,6 +35,7 @@ stdenv.mkDerivation (finalAttrs: {
     bzip2
     xz
     curl
+    libdeflate
   ];
 
   configureFlags =