diff --git a/pkgs/development/python-modules/cffi/darwin-use-libffi-closures.diff b/pkgs/development/python-modules/cffi/darwin-use-libffi-closures.diff
deleted file mode 100644
index 4ef51274aa28..000000000000
--- a/pkgs/development/python-modules/cffi/darwin-use-libffi-closures.diff
+++ /dev/null
@@ -1,29 +0,0 @@
-diff --git a/src/c/_cffi_backend.c b/src/c/_cffi_backend.c
-index 537271f..9c3bf94 100644
---- a/src/c/_cffi_backend.c
-+++ b/src/c/_cffi_backend.c
-@@ -103,11 +103,11 @@
- # define CFFI_CHECK_FFI_PREP_CIF_VAR 0
- # define CFFI_CHECK_FFI_PREP_CIF_VAR_MAYBE 0
- 
--#elif defined(__APPLE__) && defined(FFI_AVAILABLE_APPLE)
-+#elif defined(__APPLE__)
- 
--# define CFFI_CHECK_FFI_CLOSURE_ALLOC __builtin_available(macos 10.15, ios 13, watchos 6, tvos 13, *)
-+# define CFFI_CHECK_FFI_CLOSURE_ALLOC 1
- # define CFFI_CHECK_FFI_CLOSURE_ALLOC_MAYBE 1
--# define CFFI_CHECK_FFI_PREP_CLOSURE_LOC __builtin_available(macos 10.15, ios 13, watchos 6, tvos 13, *)
-+# define CFFI_CHECK_FFI_PREP_CLOSURE_LOC 1
- # define CFFI_CHECK_FFI_PREP_CLOSURE_LOC_MAYBE 1
--# define CFFI_CHECK_FFI_PREP_CIF_VAR __builtin_available(macos 10.15, ios 13, watchos 6, tvos 13, *)
-+# define CFFI_CHECK_FFI_PREP_CIF_VAR 1
- # define CFFI_CHECK_FFI_PREP_CIF_VAR_MAYBE 1
-@@ -6422,7 +6422,7 @@ static PyObject *b_callback(PyObject *self, PyObject *args)
-     else
- #endif
-     {
--#if defined(__APPLE__) && defined(FFI_AVAILABLE_APPLE) && !FFI_LEGACY_CLOSURE_API
-+#if defined(__APPLE__) && !FFI_LEGACY_CLOSURE_API
-         PyErr_Format(PyExc_SystemError, "ffi_prep_closure_loc() is missing");
-         goto error;
- #else
diff --git a/pkgs/development/python-modules/cffi/default.nix b/pkgs/development/python-modules/cffi/default.nix
index bbdd6bf08cfc..0daa51b3810a 100644
--- a/pkgs/development/python-modules/cffi/default.nix
+++ b/pkgs/development/python-modules/cffi/default.nix
@@ -44,20 +44,6 @@ else
       hash = "sha256-HDnGAWwyvEjdVFYZUOvWg24WcPKuRhKPZ89J54nFKCQ=";
     };
 
-    patches = [
-      #
-      # Trusts the libffi library inside of nixpkgs on Apple devices.
-      #
-      # Based on some analysis I did:
-      #
-      #   https://groups.google.com/g/python-cffi/c/xU0Usa8dvhk
-      #
-      # I believe that libffi already contains the code from Apple's fork that is
-      # deemed safe to trust in cffi.
-      #
-      ./darwin-use-libffi-closures.diff
-    ];
-
     nativeBuildInputs = [ pkg-config ];
 
     build-system = [ setuptools ];