diff --git a/pkgs/development/python-modules/amazon-ion/default.nix b/pkgs/development/python-modules/amazon-ion/default.nix
new file mode 100644
index 000000000000..016fa989a8ab
--- /dev/null
+++ b/pkgs/development/python-modules/amazon-ion/default.nix
@@ -0,0 +1,29 @@
+{ lib, buildPythonPackage, fetchPypi, jsonconversion, six, pytestCheckHook }:
+
+buildPythonPackage rec {
+  pname = "amazon-ion";
+  version = "0.8.0";
+
+  src = fetchPypi {
+    pname = "amazon.ion";
+    inherit version;
+    sha256 = "sha256-vtztUHSnGoPYozhwvigxEdieVtbKNfV4B5yZ4MHaWGw=";
+  };
+
+  postPatch = ''
+    substituteInPlace setup.py --replace "'pytest-runner'," ""
+  '';
+
+  propagatedBuildInputs = [ jsonconversion six ];
+
+  checkInputs = [ pytestCheckHook ];
+
+  pythonImportsCheck = [ "amazon.ion" ];
+
+  meta = with lib; {
+    description = "A Python implementation of Amazon Ion";
+    homepage = "https://github.com/amzn/ion-python";
+    license = licenses.asl20;
+    maintainers = [ maintainers.terlar ];
+  };
+}
diff --git a/pkgs/development/python-modules/ionhash/default.nix b/pkgs/development/python-modules/ionhash/default.nix
new file mode 100644
index 000000000000..4d90d572876c
--- /dev/null
+++ b/pkgs/development/python-modules/ionhash/default.nix
@@ -0,0 +1,38 @@
+{ lib, buildPythonPackage, fetchFromGitHub, fetchpatch, amazon-ion, six, pytestCheckHook }:
+
+buildPythonPackage rec {
+  pname = "ionhash";
+  version = "1.2.1";
+
+  src = fetchFromGitHub {
+    owner = "amzn";
+    repo = "ion-hash-python";
+    rev = "v${version}";
+    sha256 = "sha256-mXOLKXauWwwIA/LnF4qyZsBiF/QM+rF9MmE2ewmozYo=";
+    fetchSubmodules = true;
+  };
+
+  patches = [
+    (fetchpatch {
+      url = "https://github.com/amzn/ion-hash-python/commit/5cab56d694ecc176e394bb455c2d726ba1514ce0.patch";
+      sha256 = "sha256-P5QByNafgxI//e3m+b0oG00+rVymCsT/J4dOZSk3354=";
+    })
+  ];
+
+  postPatch = ''
+    substituteInPlace setup.py --replace "'pytest-runner'," ""
+  '';
+
+  propagatedBuildInputs = [ amazon-ion six ];
+
+  checkInputs = [ pytestCheckHook ];
+
+  pythonImportsCheck = [ "ionhash" ];
+
+  meta = with lib; {
+    description = "Python implementation of Amazon Ion Hash";
+    homepage = "https://github.com/amzn/ion-hash-python";
+    license = licenses.asl20;
+    maintainers = [ maintainers.terlar ];
+  };
+}
diff --git a/pkgs/development/python-modules/jsonconversion/default.nix b/pkgs/development/python-modules/jsonconversion/default.nix
new file mode 100644
index 000000000000..22f7fe4625d1
--- /dev/null
+++ b/pkgs/development/python-modules/jsonconversion/default.nix
@@ -0,0 +1,26 @@
+{ lib, buildPythonPackage, fetchPypi, pytestCheckHook, numpy }:
+
+buildPythonPackage rec {
+  pname = "jsonconversion";
+  version = "0.2.13";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "sha256-4hMY0N/Px+g5zn3YzNfDWPyi8Pglvd/c2N9SeC4JoZ0=";
+  };
+
+  postPatch = ''
+    substituteInPlace setup.py --replace "'pytest-runner'" ""
+  '';
+
+  checkInputs = [ pytestCheckHook numpy ];
+
+  pythonImportsCheck = [ "jsonconversion" ];
+
+  meta = with lib; {
+    description = "This python module helps converting arbitrary Python objects into JSON strings and back";
+    homepage = "https://pypi.org/project/jsonconversion/";
+    license = licenses.bsd2;
+    maintainers = [ maintainers.terlar ];
+  };
+}
diff --git a/pkgs/development/python-modules/pyqldb/default.nix b/pkgs/development/python-modules/pyqldb/default.nix
new file mode 100644
index 000000000000..a6fd8665fd14
--- /dev/null
+++ b/pkgs/development/python-modules/pyqldb/default.nix
@@ -0,0 +1,32 @@
+{ lib, buildPythonPackage, fetchFromGitHub, boto3, amazon-ion, ionhash, pytestCheckHook }:
+
+buildPythonPackage rec {
+  pname = "pyqldb";
+  version = "3.2.2";
+
+  src = fetchFromGitHub {
+    owner = "awslabs";
+    repo = "amazon-qldb-driver-python";
+    rev = "v${version}";
+    sha256 = "sha256-TKf43+k428h8T6ye6mJrnK9D4J1xpIu0QacM7lWJF7w=";
+  };
+
+  propagatedBuildInputs = [ boto3 amazon-ion ionhash ];
+
+  checkInputs = [ pytestCheckHook ];
+
+  preCheck = ''
+    export AWS_DEFAULT_REGION=us-east-1
+  '';
+
+  pytestFlagsArray = [ "tests/unit" ];
+
+  pythonImportsCheck = [ "pyqldb" ];
+
+  meta = with lib; {
+    description = "Python driver for Amazon QLDB";
+    homepage = "https://github.com/awslabs/amazon-qldb-driver-python";
+    license = licenses.asl20;
+    maintainers = [ maintainers.terlar ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 84dd3512e9de..a8fa9c95307c 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -472,6 +472,8 @@ in {
 
   altair = callPackage ../development/python-modules/altair { };
 
+  amazon-ion = callPackage ../development/python-modules/amazon-ion { };
+
   amazon_kclpy = callPackage ../development/python-modules/amazon_kclpy { };
 
   ambee = callPackage ../development/python-modules/ambee { };
@@ -4102,6 +4104,8 @@ in {
 
   iocapture = callPackage ../development/python-modules/iocapture { };
 
+  ionhash = callPackage ../development/python-modules/ionhash { };
+
   iotawattpy = callPackage ../development/python-modules/iotawattpy { };
 
   iowait = callPackage ../development/python-modules/iowait { };
@@ -4310,6 +4314,8 @@ in {
 
   json5 = callPackage ../development/python-modules/json5 { };
 
+  jsonconversion = callPackage ../development/python-modules/jsonconversion { };
+
   jsondate = callPackage ../development/python-modules/jsondate { };
 
   jsondiff = callPackage ../development/python-modules/jsondiff { };
@@ -7494,6 +7500,8 @@ in {
 
   pypytools = callPackage ../development/python-modules/pypytools { };
 
+  pyqldb = callPackage ../development/python-modules/pyqldb { };
+
   pyqrcode = callPackage ../development/python-modules/pyqrcode { };
 
   pyqt-builder = callPackage ../development/python-modules/pyqt-builder { };