diff --git a/pkgs/development/python-modules/rpy2/default.nix b/pkgs/development/python-modules/rpy2/default.nix
index 8c477e554cb6..1fd58cb565fe 100644
--- a/pkgs/development/python-modules/rpy2/default.nix
+++ b/pkgs/development/python-modules/rpy2/default.nix
@@ -89,6 +89,13 @@ buildPythonPackage rec {
 
   doCheck = !stdenv.isDarwin;
 
+  # https://github.com/rpy2/rpy2/issues/1111
+  disabledTests = [
+    "test_parse_incomplete_error"
+    "test_parse_error"
+    "test_parse_error_when_evaluting"
+  ];
+
   nativeCheckInputs = [ pytestCheckHook ];
 
   meta = {