diff --git a/pkgs/development/libraries/libressl/CVE-2021-41581.patch b/pkgs/development/libraries/libressl/CVE-2021-41581.patch
deleted file mode 100644
index 244792567192..000000000000
--- a/pkgs/development/libraries/libressl/CVE-2021-41581.patch
+++ /dev/null
@@ -1,53 +0,0 @@
-Based on upstream https://github.com/openbsd/src/commit/62ceddea5b1d64a1a362bbb7071d9e15adcde6b1
-with paths switched to apply to libressl-portable and CVS header
-hunk removed.
-
---- a/crypto/x509/x509_constraints.c
-+++ b/crypto/x509/x509_constraints.c
-@@ -339,16 +339,16 @@
- 			if (c == '.')
- 				goto bad;
- 		}
--		if (wi > DOMAIN_PART_MAX_LEN)
--			goto bad;
- 		if (accept) {
-+			if (wi >= DOMAIN_PART_MAX_LEN)
-+				goto bad;
- 			working[wi++] = c;
- 			accept = 0;
- 			continue;
- 		}
- 		if (candidate_local != NULL) {
- 			/* We are looking for the domain part */
--			if (wi > DOMAIN_PART_MAX_LEN)
-+			if (wi >= DOMAIN_PART_MAX_LEN)
- 				goto bad;
- 			working[wi++] = c;
- 			if (i == len - 1) {
-@@ -363,7 +363,7 @@
- 			continue;
- 		}
- 		/* We are looking for the local part */
--		if (wi > LOCAL_PART_MAX_LEN)
-+		if (wi >= LOCAL_PART_MAX_LEN)
- 			break;
- 
- 		if (quoted) {
-@@ -383,6 +383,8 @@
- 			 */
- 			if (c == 9)
- 				goto bad;
-+			if (wi >= LOCAL_PART_MAX_LEN)
-+				goto bad;
- 			working[wi++] = c;
- 			continue; /* all's good inside our quoted string */
- 		}
-@@ -412,6 +414,8 @@
- 		}
- 		if (!local_part_ok(c))
- 			goto bad;
-+		if (wi >= LOCAL_PART_MAX_LEN)
-+			goto bad;
- 		working[wi++] = c;
- 	}
- 	if (candidate_local == NULL || candidate_domain == NULL)
diff --git a/pkgs/development/libraries/libressl/default.nix b/pkgs/development/libraries/libressl/default.nix
index d70672f63ac3..c091a1b698d2 100644
--- a/pkgs/development/libraries/libressl/default.nix
+++ b/pkgs/development/libraries/libressl/default.nix
@@ -40,6 +40,9 @@ let
     # removing ./configure pre-config.
     preConfigure = ''
       rm configure
+      substituteInPlace CMakeLists.txt \
+        --replace 'exec_prefix \''${prefix}' "exec_prefix ${placeholder "bin"}" \
+        --replace 'libdir      \''${exec_prefix}' 'libdir \''${prefix}'
     '';
 
     inherit patches;
@@ -81,17 +84,11 @@ let
 
 in {
   libressl_3_2 = generic {
-    version = "3.2.5";
-    sha256 = "1zkwrs3b19s1ybz4q9hrb7pqsbsi8vxcs44qanfy11fkc7ynb2kr";
-    patches = [
-      ./CVE-2021-41581.patch
-    ];
+    version = "3.2.7";
+    sha256 = "112bjfrwwqlk0lak7fmfhcls18ydf62cp7gxghf4gklpfl1zyckw";
   };
   libressl_3_4 = generic {
-    version = "3.4.0";
-    sha256 = "1lhn76nd59p1dfd27b4636zj6wh3f5xsi8b3sxqnl820imsswbp5";
-    patches = [
-      ./CVE-2021-41581.patch
-    ];
+    version = "3.4.1";
+    sha256 = "0766yxb599lx7qmlmsddiw9wgminz9mc311mav5q23l0rbkflz0h";
   };
 }