diff --git a/pkgs/development/libraries/grpc/default.nix b/pkgs/development/libraries/grpc/default.nix
index 3858ac7c437f..fd39e0d2368b 100644
--- a/pkgs/development/libraries/grpc/default.nix
+++ b/pkgs/development/libraries/grpc/default.nix
@@ -21,7 +21,7 @@
 
 stdenv.mkDerivation rec {
   pname = "grpc";
-  version = "1.50.0"; # N.B: if you change this, please update:
+  version = "1.51.0"; # N.B: if you change this, please update:
     # pythonPackages.grpcio-tools
     # pythonPackages.grpcio-status
 
@@ -29,7 +29,7 @@ stdenv.mkDerivation rec {
     owner = "grpc";
     repo = "grpc";
     rev = "v${version}";
-    hash = "sha256-h79Ptx17tIMFpaaid4UGzbGDztee9JctfsEcetfude0=";
+    hash = "sha256-IOwwHwPogOtCnOAGi8JgW81JB47MlmL2vNG9g2Jg8Zo=";
     fetchSubmodules = true;
   };
 
diff --git a/pkgs/development/python-modules/grpcio-status/default.nix b/pkgs/development/python-modules/grpcio-status/default.nix
index 0f659c0a14e2..96d2b8aeb233 100644
--- a/pkgs/development/python-modules/grpcio-status/default.nix
+++ b/pkgs/development/python-modules/grpcio-status/default.nix
@@ -9,14 +9,14 @@
 
 buildPythonPackage rec {
   pname = "grpcio-status";
-  version = "1.50.0";
+  version = "1.51.0";
   format = "setuptools";
 
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "69be81c4317ec77983fb0eab80221a01e86e833e0fcf2f6acea0a62597c84b93";
+    sha256 = "5415b3fa555cd9f0dbfe51bc2b2818cf11c96b5898b103421f6df2fa65108fa2";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/grpcio-tools/default.nix b/pkgs/development/python-modules/grpcio-tools/default.nix
index 1fbdc3973799..2e1a130c07b4 100644
--- a/pkgs/development/python-modules/grpcio-tools/default.nix
+++ b/pkgs/development/python-modules/grpcio-tools/default.nix
@@ -2,11 +2,12 @@
 
 buildPythonPackage rec {
   pname = "grpcio-tools";
-  version = "1.50.0";
+  version = "1.51.0";
+  format = "setuptools";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "88b75f2afd889c7c6939f58d76b58ab84de4723c7de882a1f8448af6632e256f";
+    sha256 = "264abafefc3240aacdc6e0c7765a8a20c284f1267ae0dd899084f07694b55095";
   };
 
   postPatch = ''