diff --git a/pkgs/development/libraries/gtk/4.x.nix b/pkgs/development/libraries/gtk/4.x.nix
index 5f2301ca0e81..218efb6559fb 100644
--- a/pkgs/development/libraries/gtk/4.x.nix
+++ b/pkgs/development/libraries/gtk/4.x.nix
@@ -3,6 +3,7 @@
 , buildPackages
 , substituteAll
 , fetchurl
+, fetchpatch
 , pkg-config
 , gettext
 , graphene
@@ -68,7 +69,7 @@ in
 
 stdenv.mkDerivation rec {
   pname = "gtk4";
-  version = "4.12.2";
+  version = "4.12.3";
 
   outputs = [ "out" "dev" ] ++ lib.optionals x11Support [ "devdoc" ];
   outputBin = "dev";
@@ -80,12 +81,19 @@ stdenv.mkDerivation rec {
 
   src = fetchurl {
     url = "mirror://gnome/sources/gtk/${lib.versions.majorMinor version}/gtk-${version}.tar.xz";
-    sha256 = "L09NT5LgnyFtOGz9rdVNM9l/I6RVXWe5fez6b4Fba4E=";
+    sha256 = "FIziYvbIZIdFX7HZeTw/WLw+HaR3opYX+tsEIPWHCok=";
   };
 
   patches = [
     # https://github.com/NixOS/nixpkgs/pull/218143#issuecomment-1501059486
     ./patches/4.0-fix-darwin-build.patch
+
+    # gdk: Fix compilation on macos
+    # https://gitlab.gnome.org/GNOME/gtk/-/merge_requests/6208
+    (fetchpatch {
+      url = "https://gitlab.gnome.org/GNOME/gtk/-/commit/aa888c0b3f775776fe3b71028396b7a8c6adb1d6.patch";
+      sha256 = "sha256-Jw6BvWDX0wIs4blUiX3qdQCR574yhcaO06Vy/IqfbJo=";
+    })
   ];
 
   depsBuildBuild = [