diff --git a/pkgs/development/python-modules/adblock/default.nix b/pkgs/development/python-modules/adblock/default.nix
index 02ca5197c6d0..7dfe54fddbc4 100644
--- a/pkgs/development/python-modules/adblock/default.nix
+++ b/pkgs/development/python-modules/adblock/default.nix
@@ -1,6 +1,7 @@
 { lib
 , stdenv
 , fetchFromGitHub
+, fetchpatch
 , buildPythonPackage
 , rustPlatform
 , pkg-config
@@ -29,6 +30,15 @@ buildPythonPackage rec {
     hash = "sha256-5g5xdUzH/RTVwu4Vfb5Cb1t0ruG0EXgiXjrogD/+JCU=";
   };
 
+  patches = [
+    # https://github.com/ArniDagur/python-adblock/pull/91
+    (fetchpatch {
+      name = "pep-621-compat.patch";
+      url = "https://github.com/ArniDagur/python-adblock/commit/2a8716e0723b60390f0aefd0e05f40ba598ac73f.patch";
+      hash = "sha256-n9+LDs0no66OdNZxw3aU57ngWrAbmm6hx4qIuxXoatM=";
+    })
+  ];
+
   cargoDeps = rustPlatform.fetchCargoTarball {
     inherit src;
     name = "${pname}-${version}";