diff --git a/pkgs/development/python-modules/soxr/cmake-nanobind.patch b/pkgs/development/python-modules/soxr/cmake-nanobind.patch
new file mode 100644
index 000000000000..2f527e7a1692
--- /dev/null
+++ b/pkgs/development/python-modules/soxr/cmake-nanobind.patch
@@ -0,0 +1,16 @@
+diff --git a/CMakeLists.txt b/CMakeLists.txt
+index eb701aa..6cb4b02 100644
+--- a/CMakeLists.txt
++++ b/CMakeLists.txt
+@@ -32,6 +32,11 @@ find_package(Python 3.9
+     REQUIRED COMPONENTS Interpreter Development.Module
+     OPTIONAL_COMPONENTS Development.SABIModule)
+ 
++execute_process(
++  COMMAND "${Python_EXECUTABLE}" -m nanobind --cmake_dir
++  OUTPUT_STRIP_TRAILING_WHITESPACE OUTPUT_VARIABLE NB_DIR)
++list(APPEND CMAKE_PREFIX_PATH "${NB_DIR}")
++
+ find_package(nanobind CONFIG REQUIRED)
+ 
+ if (USE_SYSTEM_LIBSOXR)
diff --git a/pkgs/development/python-modules/soxr/default.nix b/pkgs/development/python-modules/soxr/default.nix
index 841ba83259f7..9095dcb7ae7f 100644
--- a/pkgs/development/python-modules/soxr/default.nix
+++ b/pkgs/development/python-modules/soxr/default.nix
@@ -2,51 +2,68 @@
   lib,
   buildPythonPackage,
   fetchFromGitHub,
+  pythonOlder,
 
   # build-system
-  cython,
-  numpy,
-  oldest-supported-numpy,
+  cmake,
+  nanobind,
+  ninja,
+  scikit-build-core,
   setuptools,
   setuptools-scm,
-  gnutar,
+  typing-extensions,
 
-  # native
+  # native dependencies
   libsoxr,
 
+  # dependencies
+  numpy,
+
   # tests
   pytestCheckHook,
 }:
 
 buildPythonPackage rec {
   pname = "soxr";
-  version = "0.3.7";
-  format = "pyproject";
+  version = "0.5.0.post1";
+  pyproject = true;
 
   src = fetchFromGitHub {
     owner = "dofuuz";
     repo = "python-soxr";
     rev = "refs/tags/v${version}";
     fetchSubmodules = true;
-    hash = "sha256-HGtoMfMQ5/2iEIFtik7mCrSxFnLXkSSx2W8wBul0+jk=";
+    hash = "sha256-Fpayc+MOpDUCdpoyJaIqSbMzuO0jYb6UN5ARFaxxOHk=";
   };
 
-  postPatch = ''
-    substituteInPlace setup.py \
-      --replace "SYS_LIBSOXR = False" "SYS_LIBSOXR = True"
-  '';
+  patches = [ ./cmake-nanobind.patch ];
 
   nativeBuildInputs = [
-    cython
-    gnutar
-    numpy
-    oldest-supported-numpy
-    setuptools
-    setuptools-scm
+    cmake
+    ninja
   ];
 
+  dontUseCmakeConfigure = true;
+
+  pypaBuildFlags = [
+    "--config=cmake.define.USE_SYSTEM_LIBSOXR=ON"
+  ];
+
+  build-system =
+    [
+      scikit-build-core
+      nanobind
+      setuptools
+      setuptools-scm
+    ]
+    ++ lib.optionals (pythonOlder "3.11") [
+      typing-extensions
+    ];
+
   buildInputs = [ libsoxr ];
 
+  dependencies = [ numpy ];
+
   pythonImportsCheck = [ "soxr" ];
 
   nativeCheckInputs = [ pytestCheckHook ];