diff --git a/pkgs/development/libraries/libquotient/default.nix b/pkgs/development/libraries/libquotient/default.nix
index 156375d8a2da..850d0c1caa70 100644
--- a/pkgs/development/libraries/libquotient/default.nix
+++ b/pkgs/development/libraries/libquotient/default.nix
@@ -10,9 +10,6 @@
   qtkeychain,
 }:
 
-let
-  isQt6 = lib.versions.major qtbase.version == "6";
-in
 stdenv.mkDerivation rec {
   pname = "libquotient";
   version = "0.9.1";
@@ -41,7 +38,6 @@ stdenv.mkDerivation rec {
 
   cmakeFlags = [
     "-DQuotient_ENABLE_E2EE=ON"
-    (lib.cmakeBool "BUILD_WITH_QT6" isQt6)
   ];
 
   # https://github.com/quotient-im/libQuotient/issues/551
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index c219fa51eca7..3d137225c84c 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -188,6 +188,7 @@ let
       sddm
       neochat # added 2025-07-04
       itinerary # added 2025-07-04
+      libquotient # added 2025-07-04
       ;
   };
 
@@ -1054,7 +1055,7 @@ mapAliases {
   libpseudo = throw "'libpseudo' was removed as it is broken and not maintained upstream"; # Added 2025-05-17
   libpulseaudio-vanilla = libpulseaudio; # Added 2022-04-20
   libqt5pas = libsForQt5.libqtpas; # Added 2024-12-25
-  libquotient = libsForQt5.libquotient; # Added 2023-11-11
+  libquotient = throw "'libquotient' for qt5 was removed as upstream removed qt5 support. Consider explicitly upgrading to qt6 'libquotient'"; # Converted to throw 2025-07-04
   librarian-puppet-go = throw "'librarian-puppet-go' has been removed, as its upstream is unmaintained"; # Added 2024-06-10
   librdf = throw "'librdf' has been renamed to/replaced by 'lrdf'"; # Converted to throw 2024-10-17
   librdf_raptor = throw "librdf_raptor has been remove due to failing to build and being unmaintained"; # Added 2025-04-14
diff --git a/pkgs/top-level/qt5-packages.nix b/pkgs/top-level/qt5-packages.nix
index 9d67d8024bcc..0e635efa2316 100644
--- a/pkgs/top-level/qt5-packages.nix
+++ b/pkgs/top-level/qt5-packages.nix
@@ -202,8 +202,6 @@ makeScopeWithSplicing' {
 
         libqtpas = callPackage ../development/compilers/fpc/libqtpas.nix { };
 
-        libquotient = callPackage ../development/libraries/libquotient { };
-
         libqaccessibilityclient = callPackage ../development/libraries/libqaccessibilityclient { };
 
         mapbox-gl-native = libsForQt5.callPackage ../development/libraries/mapbox-gl-native { };