diff --git a/pkgs/development/python-modules/optiland/default.nix b/pkgs/development/python-modules/optiland/default.nix
new file mode 100644
index 000000000000..23a917c6a098
--- /dev/null
+++ b/pkgs/development/python-modules/optiland/default.nix
@@ -0,0 +1,118 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  fetchpatch,
+
+  # build-system
+  hatchling,
+
+  # dependencies
+  matplotlib,
+  numba,
+  numpy,
+  pandas,
+  pyyaml,
+  requests,
+  scipy,
+  seaborn,
+  tabulate,
+  typing-extensions,
+  vtk,
+
+  # tests
+  pytestCheckHook,
+
+  # optional-dependencies
+  pyside6,
+  qtconsole,
+  torch,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "optiland";
+  version = "0.6.0";
+  pyproject = true;
+  __structuredAttrs = true;
+
+  src = fetchFromGitHub {
+    owner = "HarrisonKramer";
+    repo = "optiland";
+    tag = "v${finalAttrs.version}";
+    hash = "sha256-s+EFsfj+3VIgpqhBv8f6IblyxfxXHWnO/i1lO3bEke4=";
+  };
+
+  patches = [
+    # wayland is not supported, see:
+    # https://github.com/optiland/optiland/issues/556
+    (fetchpatch {
+      url = "https://github.com/optiland/optiland/commit/9644df6e06bd24c5a3a7cf36c8df9dd83050bccc.patch";
+      hash = "sha256-a74Z7rp3ji3+9lM8Q/RttMIzwlRBki1N2Y0YtBiVaEA=";
+    })
+    # A fixup for the above, see:
+    #
+    # - https://github.com/optiland/optiland/pull/564#discussion_r3106831922
+    # - https://github.com/optiland/optiland/pull/568
+    (fetchpatch {
+      url = "https://github.com/optiland/optiland/commit/652922bce5e1854f1d067e292422d95dee129a46.patch";
+      hash = "sha256-9O+DNbqBDDSAaRkwCy3o76lwy5MJ7WHQqzfcN1fcmnE=";
+    })
+  ];
+
+  build-system = [
+    hatchling
+  ];
+
+  dependencies = [
+    matplotlib
+    numba
+    numpy
+    pandas
+    pyyaml
+    requests
+    scipy
+    seaborn
+    tabulate
+    typing-extensions
+    vtk
+  ];
+
+  passthru = {
+    optional-dependencies = {
+      gui = [
+        pyside6
+        qtconsole
+      ];
+      torch = [
+        torch
+      ];
+    };
+  };
+
+  nativeCheckInputs = [
+    pytestCheckHook
+  ]
+  # No need for optional-dependencies.gui, as the relevant tests requiring the
+  # gui dependencies are disabled below.
+  ++ finalAttrs.finalPackage.passthru.optional-dependencies.torch;
+
+  disabledTestPaths = [
+    # From some reason, importing pyside6 during tests causes a core dump of the
+    # python interpreter, so we disable all GUI tests.
+    "tests/gui/"
+  ];
+
+  pythonImportsCheck = [
+    "optiland"
+  ];
+
+  meta = {
+    description = "Comprehensive optical design, optimization, and analysis in Python, including GPU-accelerated and differentiable ray tracing via PyTorch";
+    homepage = "https://github.com/HarrisonKramer/optiland";
+    license = lib.licenses.mit;
+    maintainers = with lib.maintainers; [ doronbehar ];
+    # Intentionally not setting optiland meta.mainProgram, as it is not
+    # functional without additional qt6 and python libraries available. See
+    # pkgs/by-name/op/optiland/package.nix for a derivation with a working GUI.
+  };
+})
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 8bd533f81366..35d5e54d3b26 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -11851,6 +11851,8 @@ self: super: with self; {
 
   optax = callPackage ../development/python-modules/optax { };
 
+  optiland = callPackage ../development/python-modules/optiland { };
+
   optimistix = callPackage ../development/python-modules/optimistix { };
 
   optimum = callPackage ../development/python-modules/optimum { };