diff --git a/pkgs/development/python-modules/gdsfactory/default.nix b/pkgs/development/python-modules/gdsfactory/default.nix
new file mode 100644
index 000000000000..b2282a04a1c0
--- /dev/null
+++ b/pkgs/development/python-modules/gdsfactory/default.nix
@@ -0,0 +1,108 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  pytestCheckHook,
+  flit-core,
+  jinja2,
+  loguru,
+  matplotlib,
+  numpy,
+  orjson,
+  pandas,
+  pydantic,
+  pydantic-settings,
+  pydantic-extra-types,
+  pyyaml,
+  qrcode,
+  rectpack,
+  rich,
+  scipy,
+  shapely,
+  toolz,
+  types-pyyaml,
+  typer,
+  kfactory,
+  watchdog,
+  freetype-py,
+  mapbox-earcut,
+  networkx,
+  scikit-image,
+  trimesh,
+  ipykernel,
+  attrs,
+  graphviz,
+  # tests
+  jsondiff,
+  jsonschema,
+  pytest-regressions,
+}:
+buildPythonPackage rec {
+  pname = "gdsfactory";
+  version = "8.18.1";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "gdsfactory";
+    repo = "gdsfactory";
+    rev = "v${version}";
+    hash = "sha256-wDz8QpRgu40FB8+otnGsHVn2e6/SWXIZgA1aeMqMhPQ=";
+  };
+
+  build-system = [ flit-core ];
+
+  dependencies = [
+    jinja2
+    loguru
+    matplotlib
+    numpy
+    orjson
+    pandas
+    pydantic
+    pydantic-settings
+    pydantic-extra-types
+    pyyaml
+    qrcode
+    rectpack
+    rich
+    scipy
+    shapely
+    toolz
+    types-pyyaml
+    typer
+    kfactory
+    watchdog
+    freetype-py
+    mapbox-earcut
+    networkx
+    scikit-image
+    trimesh
+    ipykernel
+    attrs
+    graphviz
+  ];
+
+  nativeCheckInputs = [
+    jsondiff
+    jsonschema
+    pytestCheckHook
+    pytest-regressions
+  ];
+
+  pythonRelaxDeps = [
+    "pydantic"
+    "trimesh"
+  ];
+
+  # tests require >32GB of RAM
+  doCheck = false;
+
+  pythonImportsCheck = [ "gdsfactory" ];
+
+  meta = with lib; {
+    description = "Python library to generate GDS layouts";
+    homepage = "https://github.com/gdsfactory/gdsfactory";
+    license = licenses.mit;
+    maintainers = with maintainers; [ fbeffa ];
+  };
+}
diff --git a/pkgs/development/python-modules/kfactory/default.nix b/pkgs/development/python-modules/kfactory/default.nix
new file mode 100644
index 000000000000..3652d517d048
--- /dev/null
+++ b/pkgs/development/python-modules/kfactory/default.nix
@@ -0,0 +1,77 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  pytestCheckHook,
+  setuptools,
+  setuptools-scm,
+  klayout,
+  aenum,
+  cachetools,
+  gitpython,
+  loguru,
+  pydantic,
+  pydantic-settings,
+  rectangle-packer,
+  requests,
+  ruamel-yaml-string,
+  scipy,
+  tomli,
+  toolz,
+  typer,
+  numpy,
+  ruamel-yaml,
+}:
+
+buildPythonPackage rec {
+  pname = "kfactory";
+  version = "0.21.7";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "gdsfactory";
+    repo = "kfactory";
+    rev = "v${version}";
+    sha256 = "sha256-VLhAJ5rOBKEO1FDCnlaseA+SmrMSoyS+BaEzjdHm59Y=";
+  };
+
+  build-system = [
+    setuptools
+    setuptools-scm
+  ];
+
+  dependencies = [
+    aenum
+    cachetools
+    gitpython
+    klayout
+    loguru
+    numpy
+    pydantic
+    pydantic-settings
+    rectangle-packer
+    requests
+    ruamel-yaml
+    ruamel-yaml-string
+    scipy
+    tomli
+    toolz
+    typer
+  ];
+
+  pythonImportsCheck = [ "kfactory" ];
+
+  nativeCheckInputs = [ pytestCheckHook ];
+
+  # https://github.com/gdsfactory/kfactory/issues/511
+  disabledTestPaths = [
+    "tests/test_pdk.py"
+  ];
+
+  meta = with lib; {
+    description = "KLayout API implementation of gdsfactory";
+    homepage = "https://github.com/gdsfactory/kfactory";
+    license = licenses.mit;
+    maintainers = with maintainers; [ fbeffa ];
+  };
+}
diff --git a/pkgs/development/python-modules/klayout/default.nix b/pkgs/development/python-modules/klayout/default.nix
new file mode 100644
index 000000000000..a70f384459f6
--- /dev/null
+++ b/pkgs/development/python-modules/klayout/default.nix
@@ -0,0 +1,42 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchPypi,
+  curl,
+  cython,
+  expat,
+  libpng,
+  setuptools,
+}:
+
+buildPythonPackage rec {
+  pname = "klayout";
+  version = "0.29.8";
+  pyproject = true;
+
+  src = fetchPypi {
+    inherit pname version;
+    hash = "sha256-21EPhFb/JMZdyuHDXIxhnLTpHUPxKU24cnodH9oX2q8=";
+  };
+
+  build-system = [
+    cython
+    setuptools
+  ];
+
+  buildInputs = [
+    curl
+    expat
+    libpng
+  ];
+
+  pythonImportsCheck = [ "klayout" ];
+
+  meta = with lib; {
+    description = "KLayout’s Python API";
+    homepage = "https://github.com/KLayout/klayout";
+    license = licenses.gpl3Plus;
+    maintainers = with maintainers; [ fbeffa ];
+    platforms = platforms.linux;
+  };
+}
diff --git a/pkgs/development/python-modules/rectangle-packer/default.nix b/pkgs/development/python-modules/rectangle-packer/default.nix
new file mode 100644
index 000000000000..53a58f1246b6
--- /dev/null
+++ b/pkgs/development/python-modules/rectangle-packer/default.nix
@@ -0,0 +1,46 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  setuptools,
+  cython,
+  pytestCheckHook,
+}:
+
+buildPythonPackage rec {
+  pname = "rectangle-packer";
+  version = "2.0.2";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "Penlect";
+    repo = "rectangle-packer";
+    rev = version;
+    hash = "sha256-YsMLB9jfAC5yB8TnlY9j6ybXM2ILireOgQ8m8wYo4ts=";
+  };
+
+  build-system = [
+    cython
+    setuptools
+  ];
+
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace-fail 'Cython<3.0.0' 'Cython'
+  '';
+
+  pythonImportsCheck = [ "rpack" ];
+
+  nativeCheckInputs = [ pytestCheckHook ];
+
+  preCheck = ''
+    rm -r rpack
+  '';
+
+  meta = with lib; {
+    description = "Pack a set of rectangles into a bounding box with minimum area";
+    homepage = "https://github.com/Penlect/rectangle-packer";
+    license = licenses.mit;
+    maintainers = with maintainers; [ fbeffa ];
+  };
+}
diff --git a/pkgs/development/python-modules/rectpack/default.nix b/pkgs/development/python-modules/rectpack/default.nix
new file mode 100644
index 000000000000..d469d7021ef3
--- /dev/null
+++ b/pkgs/development/python-modules/rectpack/default.nix
@@ -0,0 +1,33 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  setuptools,
+}:
+
+buildPythonPackage rec {
+  pname = "rectpack";
+  version = "0.2.2";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "secnot";
+    repo = "rectpack";
+    rev = version;
+    hash = "sha256-kU0TT3wiudcLXrT+lYPYHYRtf7aNj/IKpnYKb/H91ng=";
+  };
+
+  build-system = [ setuptools ];
+
+  # tests are base on nose
+  doCheck = false;
+
+  pythonImportsCheck = [ "rectpack" ];
+
+  meta = with lib; {
+    description = "Collection of algorithms for solving the 2D knapsack problem";
+    homepage = "https://github.com/secnot/rectpack";
+    license = licenses.asl20;
+    maintainers = with maintainers; [ fbeffa ];
+  };
+}
diff --git a/pkgs/development/python-modules/ruamel-yaml-string/default.nix b/pkgs/development/python-modules/ruamel-yaml-string/default.nix
new file mode 100644
index 000000000000..0634359f6511
--- /dev/null
+++ b/pkgs/development/python-modules/ruamel-yaml-string/default.nix
@@ -0,0 +1,32 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchPypi,
+  setuptools,
+  ruamel-yaml,
+}:
+
+buildPythonPackage rec {
+  pname = "ruamel-yaml-string";
+  version = "0.1.1";
+  pyproject = true;
+
+  src = fetchPypi {
+    inherit version;
+    pname = "ruamel.yaml.string";
+    hash = "sha256-enrtzAVdRcAE04t1b1hHTr77EGhR9M5WzlhBVwl4Q1A=";
+  };
+
+  build-system = [ setuptools ];
+
+  dependencies = [ ruamel-yaml ];
+
+  pythonImportsCheck = [ "ruamel.yaml" ];
+
+  meta = with lib; {
+    description = "Add dump_to_string/dumps method that returns YAML document as string";
+    homepage = "https://sourceforge.net/projects/ruamel-yaml-string/";
+    license = licenses.mit;
+    maintainers = with maintainers; [ fbeffa ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index eb83597b8053..3a2387ea6454 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5207,6 +5207,8 @@ self: super: with self; {
 
   gdown = callPackage ../development/python-modules/gdown { };
 
+  gdsfactory = callPackage ../development/python-modules/gdsfactory { };
+
   ge25519 = callPackage ../development/python-modules/ge25519 { };
 
   geant4 = toPythonModule (pkgs.geant4.override {
@@ -7138,6 +7140,8 @@ self: super: with self; {
     inherit (pkgs) keyutils;
   };
 
+  kfactory = callPackage ../development/python-modules/kfactory { };
+
   khanaa = callPackage ../development/python-modules/khanaa {};
 
   kicad = toPythonModule (pkgs.kicad.override {
@@ -7162,6 +7166,8 @@ self: super: with self; {
 
   klaus = callPackage ../development/python-modules/klaus { };
 
+  klayout = callPackage ../development/python-modules/klayout { };
+
   klein = callPackage ../development/python-modules/klein { };
 
   kmapper = callPackage ../development/python-modules/kmapper { };
@@ -14258,6 +14264,10 @@ self: super: with self; {
 
   recordlinkage = callPackage ../development/python-modules/recordlinkage { };
 
+  rectpack = callPackage ../development/python-modules/rectpack { };
+
+  rectangle-packer = callPackage ../development/python-modules/rectangle-packer { };
+
   recurring-ical-events = callPackage ../development/python-modules/recurring-ical-events { };
 
   recursive-pth-loader = toPythonModule (callPackage ../development/python-modules/recursive-pth-loader { });
@@ -14684,6 +14694,8 @@ self: super: with self; {
 
   ruamel-yaml-clib = callPackage ../development/python-modules/ruamel-yaml-clib { };
 
+  ruamel-yaml-string = callPackage ../development/python-modules/ruamel-yaml-string { };
+
   rubicon-objc = callPackage ../development/python-modules/rubicon-objc { };
 
   rubymarshal = callPackage ../development/python-modules/rubymarshal { };