diff --git a/pkgs/development/python-modules/manifest-ml/default.nix b/pkgs/development/python-modules/manifest-ml/default.nix
new file mode 100644
index 000000000000..e0f908b3fd4f
--- /dev/null
+++ b/pkgs/development/python-modules/manifest-ml/default.nix
@@ -0,0 +1,107 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, pythonOlder
+, numpy
+, pydantic
+, redis
+, requests
+, aiohttp
+, sqlitedict
+, tenacity
+, tiktoken
+, xxhash
+, # optional dependencies
+  accelerate
+, flask
+, sentence-transformers
+, torch
+, transformers
+, fastapi
+, uvicorn
+, pillow
+, pg8000
+, sqlalchemy
+, pytestCheckHook
+}:
+
+buildPythonPackage rec {
+  pname = "manifest-ml";
+  version = "0.1.5";
+  format = "setuptools";
+
+  disalbed = pythonOlder "3.8";
+
+  src = fetchFromGitHub {
+    owner = "HazyResearch";
+    repo = "manifest";
+    rev = "refs/tags/v${version}";
+    hash = "sha256-WKibIJv4eJ0IOCRgTl02Zusf0XNTPLBIyme6HMANr8I=";
+  };
+
+  propagatedBuildInputs = [
+    numpy
+    pydantic
+    redis
+    requests
+    aiohttp
+    sqlitedict
+    tenacity
+    tiktoken
+    xxhash
+  ] ++ lib.flatten (lib.attrValues passthru.optional-dependencies);
+
+  passthru.optional-dependencies = {
+    api = [
+      accelerate
+      # deepspeed
+      # diffusers
+      flask
+      sentence-transformers
+      torch
+      transformers
+    ];
+    app = [
+      fastapi
+      uvicorn
+    ];
+    diffusers = [
+      pillow
+    ];
+    gcp = [
+      pg8000
+      # cloud-sql-python-connector
+      sqlalchemy
+    ];
+  };
+
+  nativeCheckInputs = [
+    pytestCheckHook
+  ];
+
+  preCheck = ''
+    export HOME=$TMPDIR
+  '';
+
+  pytestFlagsArray = [
+    # this file tries importing `deepspeed`, which is not yet packaged in nixpkgs
+    "--ignore=tests/test_huggingface_api.py"
+  ];
+
+  disabledTests = [
+    # these tests have db access
+    "test_init"
+    "test_key_get_and_set"
+    "test_get"
+    # this test has network access
+    "test_retry_handling"
+  ];
+
+  meta = with lib; {
+    description = "Manifest for Prompting Foundation Models";
+    homepage = "https://github.com/HazyResearch/manifest";
+    changelog = "https://github.com/HazyResearch/manifest/releases/tag/v${version}";
+    license = licenses.asl20;
+    maintainers = with maintainers; [ natsukium ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 212e13ad4506..68742a794a1f 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5913,6 +5913,8 @@ self: super: with self; {
     inherit (pkgs.darwin.apple_sdk.frameworks) AppKit;
   };
 
+  manifest-ml = callPackage ../development/python-modules/manifest-ml { };
+
   manifestparser = callPackage ../development/python-modules/marionette-harness/manifestparser.nix { };
 
   manuel = callPackage ../development/python-modules/manuel { };