diff --git a/pkgs/development/python-modules/mypy-boto3/default.nix b/pkgs/development/python-modules/mypy-boto3/default.nix
index b2273474211d..5eeb3e0c30c7 100644
--- a/pkgs/development/python-modules/mypy-boto3/default.nix
+++ b/pkgs/development/python-modules/mypy-boto3/default.nix
@@ -962,8 +962,8 @@ in
       "sha256-CGt/WuKol9nVwLHEwNgEsQDzIBhFarJNbq30OpiK0+I=";
 
   mypy-boto3-omics =
-    buildMypyBoto3Package "omics" "1.42.74"
-      "sha256-aEOjRqLbfKfWWrJGdwGP8jJHXrORoJM9Q0hxQ+BHmUY=";
+    buildMypyBoto3Package "omics" "1.42.78"
+      "sha256-h0urK602L1j2CtD1xsUOMaXizzc2CxbttMlaSNyQNoM=";
 
   mypy-boto3-opensearch =
     buildMypyBoto3Package "opensearch" "1.42.73"