diff --git a/pkgs/development/r-modules/default.nix b/pkgs/development/r-modules/default.nix
index edddcf70765e..500bbe91aa5d 100644
--- a/pkgs/development/r-modules/default.nix
+++ b/pkgs/development/r-modules/default.nix
@@ -321,13 +321,13 @@ let
     Biostrings = [ pkgs.zlib ];
     bnpmr = [ pkgs.gsl ];
     cairoDevice = [ pkgs.gtk2.dev ];
-    Cairo = with pkgs; [ libtiff libjpeg cairo.dev x11 fontconfig.lib ];
+    Cairo = with pkgs; [ libtiff libjpeg cairo.dev xlibsWrapper fontconfig.lib ];
     Cardinal = [ pkgs.which ];
     chebpol = [ pkgs.fftw ];
     ChemmineOB = with pkgs; [ openbabel pkg-config ];
     curl = [ pkgs.curl.dev ];
     data_table = [ pkgs.zlib.dev ] ++ lib.optional stdenv.isDarwin pkgs.llvmPackages.openmp;
-    devEMF = with pkgs; [ xorg.libXft.dev x11 ];
+    devEMF = with pkgs; [ xorg.libXft.dev xlibsWrapper ];
     diversitree = with pkgs; [ gsl fftw ];
     exactextractr = [ pkgs.geos ];
     EMCluster = [ pkgs.lapack ];
@@ -346,7 +346,7 @@ let
     haven = with pkgs; [ libiconv zlib.dev ];
     h5vc = [ pkgs.zlib.dev ];
     HiCseg = [ pkgs.gsl ];
-    imager = [ pkgs.x11 ];
+    imager = [ pkgs.xlibsWrapper ];
     iBMQ = [ pkgs.gsl ];
     igraph = with pkgs; [ gmp libxml2.dev ];
     JavaGD = [ pkgs.jdk ];
@@ -644,7 +644,7 @@ let
     PING = [ pkgs.gsl ];
     RcppAlgos = [ pkgs.gmp.dev ];
     RcppBigIntAlgos = [ pkgs.gmp.dev ];
-    HilbertVisGUI = [ pkgs.gnome2.gtkmm.dev ];
+    HilbertVisGUI = [ pkgs.gtkmm2.dev ];
     textshaping = with pkgs; [ harfbuzz.dev freetype.dev fribidi libpng ];
     DropletUtils = [ pkgs.zlib.dev ];
     RMariaDB = [ pkgs.libmysqlclient.dev ];
@@ -1114,7 +1114,7 @@ let
         patchShebangs configure
       '';
 
-      R_MAKEVARS_SITE = lib.optionalString (pkgs.system == "aarch64-linux")
+      R_MAKEVARS_SITE = lib.optionalString (pkgs.stdenv.system == "aarch64-linux")
         (pkgs.writeText "Makevars" ''
           CXX14PICFLAGS = -fPIC
         '');