diff --git a/pkgs/development/python-modules/mlflow-skinny/default.nix b/pkgs/development/python-modules/mlflow-skinny/default.nix
index 9f5a818c7a82..1dd062ab67ac 100644
--- a/pkgs/development/python-modules/mlflow-skinny/default.nix
+++ b/pkgs/development/python-modules/mlflow-skinny/default.nix
@@ -40,7 +40,7 @@ buildPythonPackage (finalAttrs: {
     owner = "mlflow";
     repo = "mlflow";
     rev = "v${finalAttrs.version}";
-    hash = "sha256-OxhM+KCem0sb9cwtyzrUD/MGfoiiCfgU47qipYRDaFk=";
+    hash = "sha256-e11ZncpvThb1Nt6OH+O6Do74N3dphxBiK/HIeLQMxAw=";
   };
 
   sourceRoot = "${finalAttrs.src.name}/libs/skinny";
diff --git a/pkgs/development/python-modules/mlflow-tracing/default.nix b/pkgs/development/python-modules/mlflow-tracing/default.nix
index 9f78d2dcaa32..f819fae05c66 100644
--- a/pkgs/development/python-modules/mlflow-tracing/default.nix
+++ b/pkgs/development/python-modules/mlflow-tracing/default.nix
@@ -27,7 +27,7 @@ buildPythonPackage (finalAttrs: {
     owner = "mlflow";
     repo = "mlflow";
     rev = "v${finalAttrs.version}";
-    hash = "sha256-OxhM+KCem0sb9cwtyzrUD/MGfoiiCfgU47qipYRDaFk=";
+    hash = "sha256-e11ZncpvThb1Nt6OH+O6Do74N3dphxBiK/HIeLQMxAw=";
   };
 
   sourceRoot = "${finalAttrs.src.name}/libs/tracing";
diff --git a/pkgs/development/python-modules/mlflow/default.nix b/pkgs/development/python-modules/mlflow/default.nix
index 65baefc85c0f..45725a423f68 100644
--- a/pkgs/development/python-modules/mlflow/default.nix
+++ b/pkgs/development/python-modules/mlflow/default.nix
@@ -27,7 +27,7 @@
 
 buildPythonPackage (finalAttrs: {
   pname = "mlflow";
-  version = "3.12.0";
+  version = "3.14.0";
   format = "wheel";
   __structuredAttrs = true;
 
@@ -39,7 +39,7 @@ buildPythonPackage (finalAttrs: {
     format = "wheel";
     dist = "py3";
     python = "py3";
-    hash = "sha256-4cKO1MSFV8xSx2bxfxylgmdT3fJB1D8w+ZxF9+prPOA=";
+    hash = "sha256-2/d/fNtbXA7Fm0ZxxhcwsbkUtN/3ookuJnpUfLVFT1Y=";
   };
 
   # Nix-wrapped python populates sys.path via NIX_PYTHONPATH/site hooks,
diff --git a/pkgs/development/python-modules/mlflow/subprocess-pythonpath.patch b/pkgs/development/python-modules/mlflow/subprocess-pythonpath.patch
index 9e97218fdf92..5d13a57dffa0 100644
--- a/pkgs/development/python-modules/mlflow/subprocess-pythonpath.patch
+++ b/pkgs/development/python-modules/mlflow/subprocess-pythonpath.patch
@@ -1,6 +1,6 @@
 --- a/mlflow/server/__init__.py
 +++ b/mlflow/server/__init__.py
-@@ -471,6 +471,11 @@
+@@ -474,6 +474,11 @@
              else tempfile.mkdtemp()
          )
 +    # In Nix-packaged environments sys.path is populated by wrappers but