diff --git a/pkgs/applications/gis/spatialite-gui/default.nix b/pkgs/applications/gis/spatialite-gui/default.nix
new file mode 100644
index 000000000000..541d0da8d734
--- /dev/null
+++ b/pkgs/applications/gis/spatialite-gui/default.nix
@@ -0,0 +1,77 @@
+{ lib
+, stdenv
+, fetchurl
+, pkg-config
+, desktopToDarwinBundle
+, curl
+, freexl
+, geos
+, librasterlite2
+, librttopo
+, libspatialite
+, libwebp
+, libxlsxwriter
+, libxml2
+, lz4
+, minizip
+, openjpeg
+, postgresql
+, proj
+, sqlite
+, virtualpg
+, wxGTK
+, wxmac
+, zstd
+, Carbon
+, Cocoa
+, IOKit
+}:
+
+stdenv.mkDerivation rec {
+  pname = "spatialite-gui";
+  version = "2.1.0-beta1";
+
+  src = fetchurl {
+    url = "https://www.gaia-gis.it/gaia-sins/spatialite-gui-sources/spatialite_gui-${version}.tar.gz";
+    hash = "sha256-ukjZbfGM68P/I/aXlyB64VgszmL0WWtpuuMAyjwj2zM=";
+  };
+
+  nativeBuildInputs = [ pkg-config ]
+    ++ lib.optional stdenv.isDarwin desktopToDarwinBundle;
+
+  buildInputs = [
+    curl
+    freexl
+    geos
+    librasterlite2
+    librttopo
+    libspatialite
+    libwebp
+    libxlsxwriter
+    libxml2
+    lz4
+    minizip
+    openjpeg
+    postgresql
+    proj
+    sqlite
+    virtualpg
+    zstd
+  ] ++ lib.optional stdenv.isLinux wxGTK
+    ++ lib.optionals stdenv.isDarwin [ Carbon Cocoa IOKit wxmac ];
+
+  enableParallelBuilding = true;
+
+  postFixup = lib.optionalString stdenv.isDarwin ''
+    rm -fr $out/share
+  '';
+
+  meta = with lib; {
+    description = "Graphical user interface for SpatiaLite";
+    homepage = "https://www.gaia-gis.it/fossil/spatialite_gui";
+    license = licenses.gpl3Plus;
+    platforms = platforms.unix;
+    maintainers = with maintainers; [ sikmir ];
+    mainProgram = "spatialite_gui";
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 20265a0d10bc..372d7c93b07e 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -26478,6 +26478,11 @@ with pkgs;
     inherit (darwin.apple_sdk.frameworks) Cocoa;
   };
 
+  spatialite_gui = callPackage ../applications/gis/spatialite-gui {
+    inherit (darwin.apple_sdk.frameworks) Carbon Cocoa IOKit;
+    wxGTK = wxGTK30-gtk3;
+  };
+
   spatialite_tools = callPackage ../applications/gis/spatialite-tools { };
 
   udig = callPackage ../applications/gis/udig { };