diff --git a/pkgs/tools/misc/ipxe/default.nix b/pkgs/tools/misc/ipxe/default.nix
index dacc3416c93e..03efc1b664c5 100644
--- a/pkgs/tools/misc/ipxe/default.nix
+++ b/pkgs/tools/misc/ipxe/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, lib, fetchFromGitHub, unstableGitUpdater
+{ stdenv, lib, fetchFromGitHub, unstableGitUpdater, buildPackages
 , gnu-efi, mtools, openssl, perl, xorriso, xz
 , syslinux ? null
 , embedScript ? null
@@ -32,6 +32,9 @@ stdenv.mkDerivation rec {
   version = "unstable-2022-04-06";
 
   nativeBuildInputs = [ gnu-efi mtools openssl perl xorriso xz ] ++ lib.optional stdenv.hostPlatform.isx86 syslinux;
+  depsBuildBuild = [ buildPackages.stdenv.cc ];
+
+  strictDeps = true;
 
   src = fetchFromGitHub {
     owner = "ipxe";
@@ -51,6 +54,7 @@ stdenv.mkDerivation rec {
 
   makeFlags =
     [ "ECHO_E_BIN_ECHO=echo" "ECHO_E_BIN_ECHO_E=echo" # No /bin/echo here.
+      "CROSS=${stdenv.cc.targetPrefix}"
     ] ++ lib.optional (embedScript != null) "EMBED=${embedScript}";